Post-Fatigue Vibration: Impact on Grip and Reaction Time

NCT06949566 | Completed

• 1 other identifier: BEUFTR-8
• Study Type: interventional
• Target: 42
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to investigate the acute effects of local vibration applied after induced fatigue of the wrist flexor muscles on grip strength and upper extremity reaction time.

Conditions

Muscle Fatigue

Keywords

Local Vibration; Upper Extremity Function; Wrist Flexors; Neuromuscular Performance

Outcome Measures

Primary Outcomes (2)

• Hand Grip Strength Measurement

  Grip strength will be assessed using a JAMAR® hydraulic hand dynamometer, which has five grip positions. The test will follow American Society of Hand Therapists guidelines, with the elbow at 90° flexion. Measurements will be taken on the dominant hand. Participants will sit with their head facing forward, shoulders slightly abducted (10-20°), elbows at 90°, and wrists and hands in a neutral position. Both upper extremities will remain relaxed, and feet will be flat on the floor. Fingers will be fully extended and adducted. Participants will be instructed not to allow their hands or forearms to touch the body. The dynamometer will be adjusted to fit the participant's hand size, typically set at the second handle position.

  Change in hand grip strength from baseline following intervention or rest

• Upper Extremity Reaction Time Measurement

  Upper extremity reaction times will be recorded using the BlazePod system (Play Coyotta Ltd., Tel Aviv, Israel). Participants will begin the reaction time test while seated, with both hands placed on a table, palms facing downward, and elbows flexed at 90°, with hands positioned 40 cm apart. The BlazePod unit will be placed centrally, approximately 20 cm away from each hand. When the BlazePod lights up, participants will be instructed to respond as quickly as possible by tapping the light to turn it off. As the lights will activate randomly, participants will be required to react unpredictably and respond accordingly each time the light appears. The total test duration will be recorded at the end of the trial.

  Change in upper extremity reaction time from baseline following following intervention or rest

Other Outcomes (2)

• Fatigue Perception and Relief Sensation After Vibration or Rest

  Change in baseline fatigue perception and relief sensation following intervention or rest

• Post-Fatigue Fatigue Rating

  Change in baseline fatigue following muscle exhaustion protocol

Study Arms (3)

Sham Vibration Group

SHAM COMPARATOR

In this group, sham vibration will be administered following the muscle fatigue protocol. The vibration device will be activated but positioned close to the muscle without direct contact for a duration of 10 minutes. Participants will be told that they are receiving treatment with an electromagnetic vibration device.

Other: Sham Local Vibration

50 Hz Local Vibration Intervention Group

EXPERIMENTAL

Participants in this group will receive 50 Hz local vibration following the muscle fatigue protocol. The local vibration will be applied along the flexor carpi ulnaris muscle for a duration of 10 minutes.

Other: 50 Hz Local Vibration

100 Hz Local Vibration Intervention Group

EXPERIMENTAL

Participants in this group will receive 100 Hz local vibration following the muscle fatigue protocol. The local vibration will be applied along the flexor carpi ulnaris muscle for a duration of 10 minutes.

Other: 100 Hz Local Vibration

Interventions

100 Hz Local Vibration OTHER

Participants in this group will receive 100 Hz local vibration along the flexor carpi ulnaris muscle for a duration of 10 minutes.

100 Hz Local Vibration Intervention Group

50 Hz Local Vibration OTHER

Participants in this group will receive 50 Hz local vibration along the flexor carpi ulnaris muscle for a duration of 10 minutes.

50 Hz Local Vibration Intervention Group

Sham Local Vibration OTHER

Participants in this group will receive sham vibration following the muscle fatigue protocol. The vibration device will be turned on but held near the muscle without making contact for 10 minutes. Participants will be informed that they are being treated with an electromagnetic vibration device.

Sham Vibration Group

Eligibility Criteria

• Age: 18 Years - 25 Years
• Gender Eligibility Details: Individuals who self-identify as female.
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• \. Female individuals aged 18-25

You may not qualify if:

• Having an open wound in the area where local vibration is applied
• A history of previous or current upper extremity injury
• Use of anti-inflammatory drugs
• Having a diagnosis of epilepsy

Sponsors & Collaborators

• Bitlis Eren University: lead

Study Sites (1)

Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Bitlis Eren University

Bitlis, 13100, Turkey (Türkiye)

Location

Related Publications (14)

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  PMID: 37754971 BACKGROUND

• Jones GC, Blotter JD, Smallwood CD, Eggett DL, Cochrane DJ, Feland JB. Effect of Resonant Frequency Vibration on Delayed Onset Muscle Soreness and Resulting Stiffness as Measured by Shear-Wave Elastography. Int J Environ Res Public Health. 2021 Jul 24;18(15):7853. doi: 10.3390/ijerph18157853.

  PMID: 34360146 BACKGROUND

• Alam MM, Khan AA, Farooq M. Effects of vibratory massage therapy on grip strength, endurance time and forearm muscle performance. Work. 2021;68(3):619-632. doi: 10.3233/WOR-203397.

  PMID: 33612507 BACKGROUND

• Chwala W, Pogwizd P, Rydzik L, Ambrozy T. Effect of Vibration Massage and Passive Rest on Recovery of Muscle Strength after Short-Term Exercise. Int J Environ Res Public Health. 2021 Nov 7;18(21):11680. doi: 10.3390/ijerph182111680.

  PMID: 34770194 BACKGROUND

• Alam MM, Khan AA, Farooq M. Effect of whole-body vibration on neuromuscular performance: A literature review. Work. 2018;59(4):571-583. doi: 10.3233/WOR-182699.

  PMID: 29733043 BACKGROUND

• Percival S, Sims DT, Stebbings GK. Local Vibration Therapy, Oxygen Resaturation Rate, and Muscle Strength After Exercise-Induced Muscle Damage. J Athl Train. 2022 May 1;57(5):502-509. doi: 10.4085/1062-6050-0064.21.

  PMID: 35696601 BACKGROUND

• Liepert J, Binder C. Vibration-induced effects in stroke patients with spastic hemiparesis--a pilot study. Restor Neurol Neurosci. 2010;28(6):729-35. doi: 10.3233/RNN-2010-0541.

  PMID: 21209488 BACKGROUND

• Kerschan-Schindl K, Grampp S, Henk C, Resch H, Preisinger E, Fialka-Moser V, Imhof H. Whole-body vibration exercise leads to alterations in muscle blood volume. Clin Physiol. 2001 May;21(3):377-82. doi: 10.1046/j.1365-2281.2001.00335.x.

  PMID: 11380538 BACKGROUND

• Otadi K, Ghasemi M, Jalaie S, Bagheri H, Azizian M, Emamdoost S, Sarafraz H, Sepahvand M. A prophylactic effect of local vibration on quadriceps muscle fatigue in non-athletic males: a randomized controlled trial study. J Phys Ther Sci. 2019 Mar;31(3):223-226. doi: 10.1589/jpts.31.223. Epub 2019 Mar 19.

  PMID: 30936635 BACKGROUND

• Ishikura H. Effects of local vibration stimulation on muscle recovery and hypertrophy. J Phys Ther Sci. 2024 Aug;36(8):441-446. doi: 10.1589/jpts.36.441. Epub 2024 Aug 1.

  PMID: 39092417 BACKGROUND

• Rosenkranz K, Rothwell JC. Differential effect of muscle vibration on intracortical inhibitory circuits in humans. J Physiol. 2003 Sep 1;551(Pt 2):649-60. doi: 10.1113/jphysiol.2003.043752. Epub 2003 Jun 23.

  PMID: 12821723 BACKGROUND

• Timon R, Tejero J, Brazo-Sayavera J, Crespo C, Olcina G. Effects of whole-body vibration after eccentric exercise on muscle soreness and muscle strength recovery. J Phys Ther Sci. 2016 Jun;28(6):1781-5. doi: 10.1589/jpts.28.1781. Epub 2016 Jun 28.

  PMID: 27390415 BACKGROUND

• Fuller JT, Thomson RL, Howe PR, Buckley JD. Effect of vibration on muscle perfusion: a systematic review. Clin Physiol Funct Imaging. 2013 Jan;33(1):1-10. doi: 10.1111/j.1475-097X.2012.01161.x. Epub 2012 Aug 2.

  PMID: 23216759 BACKGROUND

• Hogan MC, Richardson RS, Kurdak SS. Initial fall in skeletal muscle force development during ischemia is related to oxygen availability. J Appl Physiol (1985). 1994 Nov;77(5):2380-4. doi: 10.1152/jappl.1994.77.5.2380.

  PMID: 7868458 BACKGROUND

Study Officials

• ömer dursun, Asst. Prof.

  Bitlis Eren University

  PRINCIPAL INVESTIGATOR

• merve tunçdemir, Asst. Prof.

  Bitlis Eren University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Masking Details: The evaluator and the researcher administering the plantar vibration intervention will be different. Patients will be blinded to their group assignment.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Asst. Prof.

Study Record Dates

• First Submitted: April 22, 2025
• First Posted: April 29, 2025
• Study Start: May 8, 2025
• Primary Completion: June 26, 2025
• Study Completion: June 26, 2025
• Last Updated: July 11, 2025

Record last verified: 2025-07

Locations

TU (1)