NCT06945211

Brief Summary

Stroke remains a major public health disease worldwide ,it usually associating with damage to the motor function and other functional disabilities. Persistent upper extremity dysfunction affects many post strokepatients and is strongly associated with decreased activities of daily living . Mirror therapy one of the rehabilitation that is beneficial for neuroplasticity .This therapy is used to improve motor function after stroke .

Trial Health

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Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
36

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 10, 2024

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

April 18, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 25, 2025

Completed
20 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 15, 2025

Completed
15 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2025

Completed
Last Updated

April 25, 2025

Status Verified

April 1, 2025

Enrollment Period

8 months

First QC Date

April 18, 2025

Last Update Submit

April 18, 2025

Conditions

Keywords

Mirror TherapyStrokeNeurorehabilitation

Outcome Measures

Primary Outcomes (1)

  • UPPER LIMB MOTOR FUNCTION

    MOTOR FUNCTION WILL BE ASSESSED USING FUGL MEYER ASSESSMENT OF UPPER LIMB AS THE MAIN OUTCOME MEASURE .

    10 weeks

Study Arms (2)

INTERVENTION GROUP A LOW INTENSITY TASK ORIENTED MIRROR THERAPY

EXPERIMENTAL

Subjects will recieve Low Intensity Task Oriented Mirror Therapy: Mirror will be placed on table perpendicular to patient in such a way that the reflection of unaffected arm to be seen. The subject will be instructed to perform movement with unaffected arm. Task oriented activities: grasping objects, handling water cups, folding towels, spoon feeding, stacking wooden blocks.

Procedure: LOW INTENSITY TASK ORIENTED MIRROR THERAPY

INTERVENTION GROUP B HIGH INTENSITY TASK ORIENTED MIRROR THERAP

EXPERIMENTAL

Subjects will receive High Intensity Task Oriented Mirror Therapy : Mirror will be placed on table perpendicular to patient in such a way that the reflection of unaffected arm to be seen. The subjects will be instructed to perform movement with unaffected arm. Task Oriented Activities: grasping objects, handling water cups, folding towels, spoon feeding, stacking wooden blocks.

Procedure: High Intensity Task Oriented Mirror Therapy

Interventions

Group A Low Intensity Task Oriented Mirror Therapy will be administered for 2 and half hour per week for 30 min a day, 10 rep five times a week for 8 weeks. Task-oriented Activities for Group A: Using Sponge Balls Reaching and Grasping Objects. Handling Water Cups(pouring water ) Wiping with Rags (cleaning a table ). Using a Spray Bottle Writing and Drawing Folding Towels Turning Pages Brushing Hair keyboard typing Grabbing and releasing a cup. Spoon Feeding Practice Drinking from a Cup Card flip activity Stacking Wooden Blocks Total number of sessions 40 , 5 days a week for 30 min with 10 reps per day for 8 consecutive weeks.

INTERVENTION GROUP A LOW INTENSITY TASK ORIENTED MIRROR THERAPY

Group B High Intensity Task Oriented Mirror Therapy will be administered for 5 hours per week for 60 min a day, 20 rep five times a week for 8 weeeks. The mode of mirror therapy will be unilateral as subjects will perform movement only on unaffected arm. Task-oriented Activities for Group B: Using Sponge Balls Reaching and Grasping Objects. Handling Water Cups(pouring water ) Wiping with Rags (cleaning a table ). Using a Spray Bottle Writing and Drawing Folding Towels Turning Pages Brushing Hair keyboard typing Grabbing and releasing a cup. Spoon Feeding Practice Drinking from a Cup Card flip activity Stacking Wooden Blocks Total number of sessions 40 , 5 days a week for 60 min with 20 reps per day for 8 consecutive weeks

INTERVENTION GROUP B HIGH INTENSITY TASK ORIENTED MIRROR THERAP

Eligibility Criteria

Age45 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Both genders.
  • Age of patient 45 years and above
  • Both ischemic and hemorrhagic stroke ( subacute and chronic stroke). Cognitive function relatively intact score \> 24 MoCA
  • The patient can sit with / without support for more than 30 min

You may not qualify if:

  • Subjects with visual impairments or unilateral neglect.
  • having global aphasia.
  • unstable medical conditions or comorbidities.
  • score 3 and above on modified ashworth scale.
  • patient with orthopedic condition or any fractures.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Foundation University College of Physical Thrapy

Islamabad, 44000, Pakistan

RECRUITING

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 18, 2025

First Posted

April 25, 2025

Study Start

September 10, 2024

Primary Completion

May 15, 2025

Study Completion

May 30, 2025

Last Updated

April 25, 2025

Record last verified: 2025-04

Locations