Investigating the Effect of Caffeine Consumption on Speech Understanding in Noise in Young Adults

NCT06942117 | Recruiting

• 2 other identifiers: 41/20251919B012442147
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Caffeine is a widely consumed substance worldwide and is often used to increase alertness and improve cognitive functions. Caffeine stimulates brain activity by binding to adenosine receptors, which increases alertness instead of sleepiness. Studies on the effects of caffeine on cognitive functions have shown that it improves basic cognitive functions such as attention, reaction time, and alertness, while a less pronounced effect is seen on sensory functions such as vision and hearing. However, no study has been found investigating the effect of caffeine consumption on understanding speech in noise. Understanding speech in noise is a skill that includes not only auditory functions but also cognitive functions. This skill is affected by cognitive elements such as selective attention and executive functions. In this context, it is thought that this study, which aims to examine the relationship between caffeine and understanding speech in noise, will contribute to the literature. 60 participants between the ages of 18-30 will be included in this study. Participants will consist of individuals without hearing loss (SSO\<25 dB nHL), no history of neurological or psychological disorders, non-smokers, and those who do not use ototoxic drugs. Participants will be randomly divided into a placebo group that consumes decaffeinated coffee and a study group that consumes coffee containing 300 mg caffeine. The Turkish Matrix Test will be administered 30 minutes after coffee consumption. In addition, participants will be asked to keep a caffeine diary for one week to determine their daily caffeine consumption and will be asked to fill out the Caffeine Use Disorder Scale. Thus, they will be divided into low and high caffeine consumption groups and their speech understanding skills in noise will be compared.

Conditions

Hearing

Outcome Measures

Primary Outcomes (1)

• Turkish Matrix Test

  The test will be administered using the Oldenburg Measurement Application (OMA) software. Using the adaptive procedure, the signal-to-noise ratio (SNR-50) at which the individual repeats the words correctly at 50% will be found. Accordingly, the noise will be given continuously, kept constant at 65 dB SPL throughout the test. The test will start at 0 dB signal-to-noise ratio (SNR). There are sentences consisting of 5 words in the test. If the participant repeats at least three of the five words presented to him/her correctly, the SNR will decrease and if he/she does not repeat at least three words correctly, the SNR will increase. A total of 20 sentences will be presented to the participants.

  Before and 30 minutes after drinking coffee

Secondary Outcomes (1)

• Caffeine Use Disorder Scale

  Before consuming caffeine.

Study Arms (2)

Experimental

EXPERIMENTAL

Approximately 280 grams of caffeine containing coffee is given.

Other: Experimental

Placebo

PLACEBO COMPARATOR

Decaffeinated coffee will be provided.

Other: Placebo

Interventions

Experimental OTHER

Approximately 280 grams of caffeine containing coffee will be given

Experimental

Placebo OTHER

Decaffeinated coffee will be given.

Placebo

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• For both groups, it was planned to include individuals who had no hearing loss (SSO\<25 dB nHL), no history of neurological or psychological disorders, were non-smokers, and did not use ototoxic drugs.

Sponsors & Collaborators

• Istanbul Aydın University: lead

Study Sites (1)

İstanbul Aydin University

Istanbul, Istanbul, Turkey (Türkiye)

RECRUITING

Central Study Contacts

Merve MERAL ÇETİNKAYA

CONTACT

+905382835187; mervemeral1@aydin.edu.tr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor

Study Record Dates

• First Submitted: April 14, 2025
• First Posted: April 24, 2025
• Study Start: April 12, 2025
• Primary Completion: September 13, 2025
• Study Completion: April 13, 2026
• Last Updated: April 24, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)