Effect of an Enhanced Recovery After Surgery Program on Outcomes After Pancreatoduodenectomy
1 other identifier
observational
170
1 country
1
Brief Summary
This study assesses whether patients with pancreatic cancer who undergo surgery experience improved outcomes following the implementation of a multidisciplinary care pathway, specifically an enhanced recovery after surgery (ERAS) program. This pathway includes various interventions in the preoperative, intraoperative, and postoperative care of these patients, all aimed at enhancing their health status and postoperative results.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jul 2019
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2019
CompletedFirst Submitted
Initial submission to the registry
April 8, 2025
CompletedFirst Posted
Study publicly available on registry
April 20, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 30, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
May 30, 2025
CompletedApril 20, 2025
April 1, 2025
5.8 years
April 8, 2025
April 16, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
impact on length of stay
total number of days spent in the hospital including any readmission
within 30 days of surgery
Secondary Outcomes (1)
impact on overall morbidity
within 30 days from surgery
Study Arms (2)
Control group
traditional perioperative care
ERAS group
enhanced recovery after surgery perioperative care
Interventions
ERAS group follows the enhanced recovery after surgery program which involves 20 elements
Eligibility Criteria
Patients undergoing pancreatic surgery in two pancreatic cancer referral centers in central Greece, namely the University Hospital of Larissa, and IASO Thessalias general hospital
You may qualify if:
- adult patients
- diagnosis of pancreatic cancer
- elective open pancreatic surgery
You may not qualify if:
- age \<18 years
- emergency pancreatic surgery
- other surgical procedures
- missing data
- lost to follow-up
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Thessaly
Larissa, Greece
Related Publications (2)
Cardini B, Primavesi F, Maglione M, et al. Outcomes following pancreatic resections-results and challenges of an Austrian university hospital compared to nationwide data and international centres. Eur Surg (2019) 51:81-89. https://doi.org/10.1007/s10353-019-0585-x
BACKGROUNDLau CS, Chamberlain RS. Enhanced Recovery After Surgery Programs Improve Patient Outcomes and Recovery: A Meta-analysis. World J Surg. 2017 Apr;41(4):899-913. doi: 10.1007/s00268-016-3807-4.
PMID: 27822725BACKGROUND
Related Links
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
DESPOINA LIOTIRI, MD, DESAIC, EDRA, MSc, PhD(c)
University of Thessaly
- PRINCIPAL INVESTIGATOR
ATHINA SAMARA, MD, MSc, PhD(c)
University of Thessaly
- PRINCIPAL INVESTIGATOR
NIKOLAOS BEIS, MD
University of Thessaly
- STUDY CHAIR
DIMITRIS ZACHAROULIS, PROFESSOR OF SURGERY
University of Thessaly
- PRINCIPAL INVESTIGATOR
Alexandros Diamantis, MD, MSc, PhD
University of Thessaly
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- OTHER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Dr
Study Record Dates
First Submitted
April 8, 2025
First Posted
April 20, 2025
Study Start
July 1, 2019
Primary Completion
April 30, 2025
Study Completion
May 30, 2025
Last Updated
April 20, 2025
Record last verified: 2025-04