NCT06933979

Brief Summary

This retrospective study was carried out on pre and posttreatment digital standardized panoramic radiographs of 30 cases previously orthodontically treated with four first premolar extraction.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Feb 2025

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 23, 2025

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

March 26, 2025

Completed
23 days until next milestone

First Posted

Study publicly available on registry

April 18, 2025

Completed
2 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 20, 2025

Completed
5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

April 25, 2025

Completed
Last Updated

April 18, 2025

Status Verified

April 1, 2025

Enrollment Period

2 months

First QC Date

March 26, 2025

Last Update Submit

April 16, 2025

Conditions

Third Molar

Keywords

orthodontic treatmentpremolar extraction

Outcome Measures

Primary Outcomes (1)

  • Assessment of mandibular third molar positional variation

    measure angles:• LA-ISL: The inward angle (towards the 2nd molar) between long axis of mandibular third molar and the inter-sigmoid line (line connecting the deepest point of the right and left sigmoid notch of the mandible). • LA-IMB: The inward angle between long axis of mandibular third molar and the inferior border of the mandible.

    2 years

Eligibility Criteria

Age14 Years - 18 Years
Sexall
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Sample size calculation estimated the minimum total required sample size (n) was found to be (27). The sample size was increased to (30) account for sample variability and to improve the robustness of statistical testing

You may qualify if:

  • \- class I malocclusion cases (0 \< ANB \< 4) with moderate crowding

You may not qualify if:

  • Absence of all permanent teeth including mandibular third molars.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fayoum University

Al Fayyum, 63514, Egypt

Location

Related Publications (1)

  • Zarin DA, Tse T, Williams RJ, Califf RM, Ide NC. The ClinicalTrials.gov results database--update and key issues. N Engl J Med. 2011 Mar 3;364(9):852-60. doi: 10.1056/NEJMsa1012065.

    PMID: 21366476RESULT

Study Officials

  • Shereen A Mahlawy, PHD

    lecturer of orthodontics, faculty of dentistry, Fayoum university

    PRINCIPAL INVESTIGATOR

  • clinical cT trial

    Clinical trials.gov

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
lecturer

Study Record Dates

First Submitted

March 26, 2025

First Posted

April 18, 2025

Study Start

February 23, 2025

Primary Completion

April 20, 2025

Study Completion

April 25, 2025

Last Updated

April 18, 2025

Record last verified: 2025-04

Locations

EG(1)