Using Ecological Momentary Assessment to Develop an Adaptive Psychological Intervention for Young Adults With Chronic Pain

NCT06932432 | Recruiting

• 1 other identifier: K23AT012901
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to determine real-time contextual vulnerabilities associated with pain in young adults to inform ideal treatment targets for a just-in-time adaptive intervention (JITAI). The main question it aims to answer is:

• What contextual factors and vulnerabilities will predict momentary, next-day, and weekly pain severity? 50 young adults, ages 18-25 with a diagnosis of childhood-onset primary chronic pain, will complete 1) baseline questionnaires on REDCap to collect data on sociodemographics, medical history and treatment, psychological health (i.e., current mood symptoms and previous psychiatric conditions/treatment), and pain (e.g., duration, location) and 2) a 28-day EMA via mobile app to collect survey data on dynamic factors.

Conditions

Chronic Pain

Keywords

EMA study; childhood onset chronic pain; Young adult; Cannabis use; Real-time predictors; Health outcomes

Outcome Measures

Primary Outcomes (2)

• Momentary Pain intensity

  One item from the Brief Pain Inventory will assess momentary pain intensity (yes/no), followed by "How much pain do you feel on average?" (11-point NRS)

  Three times a day for 28 days

• Momentary Pain interference

  Two items from the Brief Pain Inventory will assess pain interference with enjoyment in life, and general activity. Higher scores indicate more interference.

  Three times a day for 28 days

Other Outcomes (13)

• Nightly sleep quality

  Once a day for 28 days (morning)

• Momentary Social Company

  Three times per day for 28 days

• Momentary Location

  Three times a day for 28 days

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Seattle Children's Hospital outpatient specialty clinics

You may qualify if:

• ages 18-25
• diagnosis of childhood-onset chronic pain who were seen for an initial evaluation at Seattle Children's Hospital outpatient specialty clinics.

You may not qualify if:

• not fluent in English
• does not have regular access to the internet and access to a smartphone device (to complete EMA questions)
• presence of chronic disease or serious medical illness (e.g., arthritis, cancer, diabetes)
• serious cognitive impairment or developmental disorder (e.g., autism, intellectual disability)

Sponsors & Collaborators

• Seattle Children's Hospital: lead
• National Center for Complementary and Integrative Health (NCCIH): collaborator

Study Sites (1)

Seattle Children's Hospital

Seattle, Washington, 98101, United States

RECRUITING

MeSH Terms

Conditions

Chronic Pain

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Caitlin Murray, PhD

CONTACT

206-884-0147; caitlin.murray@seattlechildrens.org

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: April 10, 2025
• First Posted: April 17, 2025
• Study Start: December 1, 2024
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2027
• Last Updated: April 27, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)