Screening of Lactose Intolerance Among IBS Patients Diarrhea Dominant

NCT06931379 | Not Yet Recruiting

• 1 other identifier: Screening of lactose intolera
• Study Type: observational
• Target: 70
• Locations: 0 countries
• Sites: N/A

Brief Summary

This cross-sectional study aims to determine the prevalence of lactose intolerance among patients with chronic diarrhea, assess its correlation with age and gender, and evaluate common symptoms in affected patients. The study will collect demographic data, conduct lactose intolerance testing via PCR, and use a symptom questionnaire.

Conditions

Lactose Intolerance

Keywords

lactose intolerance; chronic diarrhea

Outcome Measures

Primary Outcomes (1)

• Prevalence data on lactose intolerance in patients with IBS diarrhea dominant.

  The primary outcome is to determine the percentage of patients with chronic diarrhea who test positive for lactose intolerance using PCR testing.

  1 year

Study Arms (1)

adult patients aged 18-70 years diagnosed as IBS diarrhea dominant

The target population comprises individuals who meet the following inclusion criteria: Adults aged between 18 and 70 years. Diagnosed with IBS diarrhea dominant Both males and females are eligible for participation.

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study population consists of adult patients aged 18-70 years diagnosed with chronic diarrhea lasting more than four weeks. Both male and female participants are included. Participants will be recruited from a single healthcare center. They will undergo comprehensive assessments, including demographic profiling, medical history review, and diagnostic testing for lactose intolerance using PCR. The diversity in age and gender ensures that potential correlations with these variables can be analyzed.

You may qualify if:

• All Patients with IBS diarrhea dominant type meet Rome criteria attending at Al-Rajhy University Hospital during 6 months (from march to September). A patient must have recurrent abdominal pain (at least 1 day per week in the last 3 months) associated with at least two of the following:
• Related to defecation (pain improves or worsens with bowel movements).
• Change in stool frequency (diarrhea or constipation).
• Change in stool form (appearance) (loose, watery, hard, or lumpy).
• Patients aged \>18 years.
• Both males and females

You may not qualify if:

• patient aged\<18 years old.
• Patients with chronic diarrhea don't meet Rome criteria
• patients with malignancies

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Lactose Intolerance

Condition Hierarchy (Ancestors)

Malabsorption Syndromes; Intestinal Diseases; Gastrointestinal Diseases; Digestive System Diseases; Carbohydrate Metabolism, Inborn Errors; Metabolism, Inborn Errors; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident at the tropical medicine department

Study Record Dates

• First Submitted: April 9, 2025
• First Posted: April 17, 2025
• Study Start: January 1, 2026
• Primary Completion (Estimated): January 1, 2027
• Study Completion (Estimated): February 1, 2027
• Last Updated: January 6, 2026

Record last verified: 2026-01