NCT06924164

Brief Summary

External snapping hip is characterised by an audible and painful snap during hip movement among physical active people around 15-40 years old. Progressive resistance training has been suggested as a new potential treatment path in treating patients with external snapping hip. The investigators conducted a feasibility study and found that patients reported less pain and improved their physical function, quality of life and muscle strength after 12 weeks of progressive resistance training. The overall aim of the project is to compare hip pain in patients with external snapping hip treated with progressive resistance training to a wait-and-see approach, in a randomised controlled trial. This study has the potential to establish a new and specific treatment option for patients with external snapping hip, to be used nationally and internationally.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
11mo left

Started Jul 2025

Geographic Reach
1 country

13 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress49%
Jul 2025Apr 2027

First Submitted

Initial submission to the registry

March 28, 2025

Completed
14 days until next milestone

First Posted

Study publicly available on registry

April 11, 2025

Completed
3 months until next milestone

Study Start

First participant enrolled

July 1, 2025

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2027

Last Updated

July 10, 2025

Status Verified

July 1, 2025

Enrollment Period

1.8 years

First QC Date

March 28, 2025

Last Update Submit

July 4, 2025

Conditions

Keywords

External snapping hipProgressive resistance trainingCoxa saltans externalExercise

Outcome Measures

Primary Outcomes (1)

  • HAGOS Pain

    The HAGOS is a patient-reported questionnaire consisting of six different subscales. The pain subscale consists of 10 questions, which are all answered using standardised answer options following a 0-4-point Likert Scale. The scores are transformed into a subscale score ranging from 0 (worst) to 100 (best). A minimal clinically relevant difference of the HAGOS pain subscale has been reported to be 9.7 points among a group of patients undergoing hip arthroscopy for femoroacetabular impingement.

    Baseline, week 6, week 12 and week 24

Secondary Outcomes (7)

  • HAGOS

    Baseline, week 6, week 12 and week 24

  • UCLA-AS

    Baseline, week 12 and week 24

  • GPE

    Baseline, week 12 and week 24

  • Single leg hop test

    Baseline, week 12 and week 24

  • 30 second unilateral sit-to-stand test

    Baseline, week 12 and week 24

  • +2 more secondary outcomes

Other Outcomes (4)

  • EQ-5D-5L

    Baseline, week 12 and week 24

  • iPCQ

    Baseline, week 12 and week 24

  • HUQ

    Baseline, week 12 and week 24

  • +1 more other outcomes

Study Arms (2)

Control group: Wait and see approach

OTHER

The control group are randomized to 12 weeks of waiting time followed by 12 weeks of progressive resistance training.

Other: Progressive resistance trainingBehavioral: Waiting time

Intervention group: progressive resistance training

EXPERIMENTAL

The intervention group are randomized to 12 weeks of progressive resistance training followed by 12 weeks of self guided exercise

Other: Progressive resistance trainingBehavioral: Self guided exercise

Interventions

The progressive resistance program consist of a five-minute aerobic warm-up on either an ergometer bike, treadmill or rowing machine followed by six resistance training exercises: landmine twist, walking lunges, leg press, hip abduction, hip adduction and hip flexion. All training sessions (three per week) will be supervised for the first two weeks. After that, there will be one weekly supervised training session and two self-directed sessions. The subjects will be scheduled for 36 training sessions over 12 weeks, of which 16 will be supervised. Each training session is designed based on the findings from the feasibility study and is expected to last approximately one hour. If a subject cannot perform all scheduled sessions in a week, additional sessions will be planned for the following week to obtain the 16 supervised sessions.

Also known as: Exercise therapy
Control group: Wait and see approachIntervention group: progressive resistance training
Waiting timeBEHAVIORAL

12 weeks of waiting time

Also known as: Waitlist, Wait
Control group: Wait and see approach

12 weeks of self guided exercise

Also known as: Wait, Self training
Intervention group: progressive resistance training

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age 18-40 years (10)
  • Experienced lateral hip joint "snapping" with pain discomfort within the last 14 days
  • Able to demonstrate the audible and/or visible lateral "snapping" during lateral hip joint movementor popping sound when the hip joint moves
  • Capable of commuting to the training facility
  • Proficient in reading and understanding Danish or English

You may not qualify if:

  • Previous surgery on the affected hip
  • Planned surgery on lower extremities within the trial period
  • Anterior or medial hip discomfort that substantially exceeds the lateral hip discomfort
  • Any contraindication to exercise
  • Neurological, rheumatoid, or mental conditions affecting the hip function
  • Ongoing active cancer treatment
  • Planned vacation for more than 14 days within the intervention period
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (13)

Aalborg Universitetshospital

Aalborg, 9000, Denmark

NOT YET RECRUITING

Aarhus University Hospital

Aarhus N, 8200, Denmark

RECRUITING

Rigshospitalet

Copenhagen, 2100, Denmark

NOT YET RECRUITING

Bispebjerg og Frederiksberg Hospital

Copenhagen, 2400, Denmark

NOT YET RECRUITING

Regionshospitalet Gødstrup

Herning, 7400, Denmark

NOT YET RECRUITING

Nordsjællands Hospital - Hillerød

Hillerød, 3400, Denmark

NOT YET RECRUITING

Regionshospitalet Horsens

Horsens, 8700, Denmark

RECRUITING

Hvidovre Hospital

Hvidovre, 2650, Denmark

NOT YET RECRUITING

Sjællands Universitetshospital - Køge

Køge, 4600, Denmark

NOT YET RECRUITING

Næstved, Slagelse og Ringsted Hospital

Næstved, 4700, Denmark

NOT YET RECRUITING

Odense Universitetshospital

Odense, 5000, Denmark

NOT YET RECRUITING

Regionshospitalet Randers

Randers, 8930, Denmark

NOT YET RECRUITING

Sygehus Lillebælt - Vejle

Vejle, 7100, Denmark

NOT YET RECRUITING

MeSH Terms

Conditions

Motor Activity

Interventions

Exercise TherapyWaiting Lists

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

RehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesAppointments and SchedulesOrganization and AdministrationHealth Services Administration

Study Officials

  • Stig S Jakobsen, PhD

    Department of Orthopedic Surgery, Aarhus University Hospital, DK

    STUDY DIRECTOR
  • Lisa U Tønning, MHSc

    Department of Orthopedic Surgery, Aarhus University Hospital, DK

    PRINCIPAL INVESTIGATOR
  • Inger Mechlenburg, DMSc

    Department of Clinical Medicine, Aarhus University, DK

    STUDY DIRECTOR
  • Ulrik Dalgas, PhD

    Department of Public Health, Sports, Aarhus University, DK

    STUDY DIRECTOR
  • Troels Kjeldsen, PhD

    Department of Orthopedic Surgery, Aarhus University Hospital, DK

    STUDY DIRECTOR
  • Cara Lewis, PhD

    Department of Physical Therapy, Boston University, Boston, US

    STUDY DIRECTOR
  • Martin Lamm, MSc

    Department of Orthopedic Surgery, Aarhus University Hospital, DK

    STUDY DIRECTOR
  • Joanne L Kemp, PhD

    La Trobe Sport and Exercise Medicine Research Centre, La Trobe University, Melbourne, Australia

    STUDY DIRECTOR

Central Study Contacts

Lisa U Tønning, MHSc

CONTACT

Inger Mechlenburg, DMSc

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 28, 2025

First Posted

April 11, 2025

Study Start

July 1, 2025

Primary Completion (Estimated)

April 1, 2027

Study Completion (Estimated)

April 1, 2027

Last Updated

July 10, 2025

Record last verified: 2025-07

Data Sharing

IPD Sharing
Will share

Anonymized patient-level data will be made available if required by the scientific journal, in which the results of the trial are published. Additionally, researchers presenting a justified cause for receiving the data can obtain it after a data access agreement has been signed.

Shared Documents
STUDY PROTOCOL, SAP, ICF, ANALYTIC CODE
Time Frame
Data will be available after publication of the trial upon reasonably request.
Access Criteria
Applications for data access will be reviewed by the author group. The applicant will be required to sign a data access agreement.

Locations