NCT06922370

Brief Summary

Patients with clinically and genetically confirmed Gitelman Syndrome are screened for CPPD, and the clinical and radiographic manifestations are collected and analyzed.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
120

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Nov 2021

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2021

Completed
3.4 years until next milestone

First Submitted

Initial submission to the registry

April 3, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 10, 2025

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2025

Completed
Last Updated

April 10, 2025

Status Verified

March 1, 2025

Enrollment Period

4 years

First QC Date

April 3, 2025

Last Update Submit

April 3, 2025

Conditions

Gitelman SyndromeCPPD - Calcium Pyrophosphate Deposition Disease

Outcome Measures

Primary Outcomes (1)

  • The presence of chondrocalcinosis

    The presence of chondrocalcinosis on conventional radiograph or computed tomography in patients with Gitelman Syndrome

    From the enrollment to the performance of the CPPD screen

Study Arms (1)

Patients with Gitelman Syndrome

Patients with clinically and genetically confirmed Gitelman syndrome.

Diagnostic Test: conventional radiograph or computed tomography

Interventions

conventional radiograph or computed tomographyDIAGNOSTIC_TEST

patients with gitelman syndrome evaluated with conventional radiograph or computed tomography

Patients with Gitelman Syndrome

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients clinically and genetically confirmed with Gitelman Syndrome

You may qualify if:

  • Patients confirmed with Gitelman Syndrome

You may not qualify if:

  • Patients with other confounding situations such as Bartter Syndrome, hyperparathyroidism

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

the second affiliated hospital, Zhejiang University School of medicine

Hangzhou, Zhejiang, 310005, China

RECRUITING

MeSH Terms

Conditions

Gitelman SyndromeChondrocalcinosis

Interventions

Tomography, X-Ray Computed

Condition Hierarchy (Ancestors)

Renal Tubular Transport, Inborn ErrorsKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesArthritisJoint DiseasesMusculoskeletal DiseasesCrystal Arthropathies

Intervention Hierarchy (Ancestors)

Image Interpretation, Computer-AssistedDiagnostic ImagingDiagnostic Techniques and ProceduresDiagnosisRadiographic Image EnhancementImage EnhancementPhotographyRadiographyTomography, X-RayTomography

Central Study Contacts

Lijun Mou

CONTACT

+86-0571-89713751moulj511@zju.edu.cn

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 3, 2025

First Posted

April 10, 2025

Study Start

November 1, 2021

Primary Completion

November 1, 2025

Study Completion

December 1, 2025

Last Updated

April 10, 2025

Record last verified: 2025-03

Locations

CN(1)