Mobilization With Movement Versus Joint-Specific Manipulation in De Quervain's Tenosynovitis

NCT06918158 | Completed

• 1 other identifier: REC-01001 Khaista Bacha
• Study Type: interventional
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

A comparative study on the effectiveness of mobilization with movement (MWM) versus joint-specific manipulation (JSM) in patients with De Quervain's tenosynovitis typically aims to assess how each technique impacts pain relief and functional improvement. De Quervain's tenosynovitis is an inflammation of the tendons around the thumb and wrist, often causing pain, swelling, and difficulty in performing everyday tasks. The study would likely compare the two interventions by measuring pain levels, range of motion, and overall functional outcomes before and after treatment. MWM involves applying specific, controlled movements while the patient is actively engaging in their joint motion, targeting the tissue's mobility and reducing pain. JSM, on the other hand, focuses on manipulating the joint directly to restore normal function, specifically targeting the wrist and thumb regions affected by the condition.

Conditions

Tenosynovitis

Keywords

Tenosynovitis

Outcome Measures

Primary Outcomes (1)

• Pain Reduction - Measured using the Numeric Pain Rating Scale (NPRS) (0-10 scale).

  Pain intensity will be assessed using the Numeric Pain Rating Scale (NPRS), a validated tool where participants rate their pain on a scale from 0 no pain to 10 worst possible pain.

  6 Months

Secondary Outcomes (1)

• Wrist Function - Assessed with the Patient-Rated Wrist Evaluation (PRWE) (0-100 scale).

  6months

Other Outcomes (1)

• Clinical Signs - Evaluated using Finkelstein's Test (Positive/Negative).

  6 months

Study Arms (2)

Joint-specific Manipulation

EXPERIMENTAL

Group A

Other: Joint Specific Manipulation

Mobilization with Movement

PLACEBO COMPARATOR

Group B

Other: Mobilization with Movement

Interventions

Mobilization with Movement OTHER

Mobilization with Movement * The proximal row of carpals glides passively radially. * Active thumb and wrist movements superimposed on the glide. Therapeutic excercises: * Ball Toss * Static web gripping * Gentle ROM activities to maintain mobility * Isometric exercises in all direction

Mobilization with Movement

Joint Specific Manipulation OTHER

Joint Specific Manipulation * High-velocity, low-amplitude thrust to the first carpometacarpal joint * Radiocarpal wrist mobilization .Grade III-IV applied at end range. 2. Therapeutic excercises: * Ball Toss * Static web gripping * Gentle ROM activities to maintain mobility * Isometric exercises in all direction Ergonomics modifications

Joint-specific Manipulation

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age between 25-45 years.
• Positive Finkelstein test.
• Pain over the first dorsal compartment.
• Limited wrist and thumb function.
• Willingness to take part and adhere to the study's guidelines.

You may not qualify if:

• Previous surgery of wrist or thumb.
• Presence of neurological symptoms like numbness, weakeness.
• Rheumatological conditions like rheumatoid arthritis.
• Pregnancy.
• Presence of wrist fracture or osteoporosis.
• Carpel tunnel syndrome.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Riphah international University Malakand Campus

Malakand, KPK, 23060, Pakistan

Location

MeSH Terms

Conditions

Tenosynovitis

Interventions

Movement

Condition Hierarchy (Ancestors)

Tendinopathy; Muscular Diseases; Musculoskeletal Diseases

Intervention Hierarchy (Ancestors)

Physiological Phenomena; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Dr.Nadeem Ahmad, MS

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: RCT

Study Record Dates

• First Submitted: February 20, 2025
• First Posted: April 9, 2025
• Study Start: February 17, 2025
• Primary Completion: February 17, 2025
• Study Completion: February 17, 2025
• Last Updated: April 25, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)