NCT06917521

Brief Summary

Ventilator-associated pneumonia (VAP) is the most frequent infection in the intensive care setting. For VAP there is currently no reliable diagnostic criteria. We aimed with the present study, using data from the mechanical ventilator to identify early this infection using artificial intelligence methods .

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
76

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jul 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2023

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2025

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

April 1, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 8, 2025

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 15, 2025

Completed
Last Updated

August 24, 2025

Status Verified

August 1, 2025

Enrollment Period

1.7 years

First QC Date

April 1, 2025

Last Update Submit

August 22, 2025

Conditions

Ventilator Associated Pneumonia ( VAP)

Outcome Measures

Primary Outcomes (1)

  • Early identification of VAP

    Sensitivity, specificity, AUROC and AUPRC

    From July 2023 to Mars 2025

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All consecutive adult patients admitted to our ICU requiring invasive respiratory support for at least 48 hours will be enrolled

You may qualify if:

  • adult patients admitted to our ICU requiring invasive respiratory support for at least 48 hours

You may not qualify if:

  • previuos pneumonia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ospedale civico Lugano

Lugano, Canton Ticino, 6900, Switzerland

Location

MeSH Terms

Conditions

Pneumonia, Ventilator-Associated

Condition Hierarchy (Ancestors)

Healthcare-Associated PneumoniaCross InfectionInfectionsPneumoniaRespiratory Tract InfectionsLung DiseasesRespiratory Tract DiseasesIatrogenic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 1, 2025

First Posted

April 8, 2025

Study Start

July 1, 2023

Primary Completion

March 1, 2025

Study Completion

June 15, 2025

Last Updated

August 24, 2025

Record last verified: 2025-08

Locations

CH(1)