The Relationship Between Umbilical Cord Coiling Index and Fetal Cardiac Functions.

NCT06915051 | Completed

• 1 other identifier: SEAH-COİLİNG
• Study Type: observational
• Target: 202
• Locations: 1 country
• Sites: 1

Brief Summary

The maximum efficiency of umbilical cord blood flow depends on a specific number of coils. With modern ultrasound techniques, investigators can now detect cord abnormalities even before birth. In recent years, there has been a renewed interest in the umbilical cord, and several articles have been published regarding the number of coils.In this study, the relationship between the umbilical cord coiling index and fetal cardiac functions was evaluated.

Conditions

Umbilical Cord Coiling Index and Fetal Cardiac Functions

Keywords

Umbilical cord coiling index; fetal cardiac functions; umbilical cord; fetal circulation

Outcome Measures

Primary Outcomes (1)

• The correlation between the fetal umbilical cord coiling number and the concurrently performed fetal echocardiography findings.

  This study will be a single-center study conducted on two hundred randomly selected pregnant women with uncomplicated singleton pregnancies in the late second trimester (20-24 weeks) who visit our hospital's perinatology outpatient clinic for routine prenatal check-ups. The umbilical cord coiling number and fetal cardiac function measurements will be performed within one hour by the same maternal-fetal medicine specialist.To optimize the quality of Doppler waveforms when assessing vascular structures, measurements will be obtained in the absence of uterine contractions and fetal activity, with an insonation angle as close to zero as possible and less than 30.Three parameters will be used to assess cardiac function: 1. Diastolic function 2. Systolic function 3. Both systolic and diastolic function

  The correlation between the fetal umbilical cord coiling index and the echocardiographic findings of the fetus within the first hour will be investigated.

Study Arms (1)

This is a single-center study conducted on 200 randomly selected pregnant women with uncomplicated.

Diagnostic Test: Determining the relationship between the coiling number and fetal echocardiography findings.

Interventions

Determining the relationship between the coiling number and fetal echocardiography findings. DIAGNOSTIC_TEST

Fetal echocardiography findings to be performed simultaneously with the determination of the coiling number.

This is a single-center study conducted on 200 randomly selected pregnant women with uncomplicated.

Eligibility Criteria

• Age: 18 Years - 50 Years
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Singleton uncomplicated pregnancies between 20-24 weeks seeking routine antenatal care will be included.

You may qualify if:

• Singleton uncomplicated pregnancies between 20-24 weeks seeking routine antenatal care.

You may not qualify if:

• Multiple pregnancy
• Preterm rupture of membranes
• Chorioamnionitis
• Placental abruption
• Severe fetal growth restriction
• Congenital anomalies of the fetus
• Preeclampsia
• Oligohydramnios
• Maternal diabetes.

Sponsors & Collaborators

• Sanliurfa Education and Research Hospital: lead

Study Sites (1)

Sanliurfa Education and Research Hospital

Sanliurfa, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Persistent Fetal Circulation Syndrome

Condition Hierarchy (Ancestors)

Hypertension, Pulmonary; Lung Diseases; Respiratory Tract Diseases; Infant, Newborn, Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Target Duration: 4 Months
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 25, 2025
• First Posted: April 8, 2025
• Study Start: March 1, 2025
• Primary Completion: June 15, 2025
• Study Completion: August 30, 2025
• Last Updated: November 18, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)