Evaluation of Central Corneal Thickness in Patients With Vernal Keratoconjunctivitis Using Topical Steroids

NCT06913790 | Active Not Recruiting DMC

• 1 other identifier: MSRSW/Batch-Fall23/808
• Study Type: observational
• Target: 34
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective observational cohort study aims to assess changes in central corneal thickness (CCT) in vernal keratoconjunctivitis (VKC) patients using topical steroids. Data will be collected from tertiary care hospitals such as Al-Mustafa eye hospital and Jinnah Hospital, Lahore.

Conditions

Vernal Keratoconjunctivitis

Outcome Measures

Primary Outcomes (1)

• Slit Lamp Test

  A slit lamp exam, a common eye test, uses a microscope and a focused light beam to examine the front and back of the eye, aiding in the diagnosis of various conditions, and often involves scoring or grading for certain aspects like cell and flar

  12 Months

Eligibility Criteria

• Age: 5 Years - 25 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

This prospective observational cohort study aims to assess changes in central corneal thickness (CCT) in vernal keratoconjunctivitis (VKC) patients using topical steroids. Data will be collected from tertiary care hospitals such as Al-Mustafa eye hospital and Jinnah Hospital, Lahore

You may qualify if:

• Young adults aged between 5-25 years
• Confirmed diagnosis of VKC
• Currently prescribe topical steroid e.g, dexamethasone, prednisolone
• No prior history of corneal surgery or trauma
• Willing to attend follow-up visits and comply with the treatment protocol.

You may not qualify if:

• History of ocular surgery or trauma
• Presence of other corneal pathologies (e.g., Keratoconus)
• Systemic immunosuppressant use or history of systemic steroid use in the past 06 months
• Use of other medications that could influence corneal thickness e.g, antiglaucoma drugs
• Contact lens use within 1 month prior to the study
• Severe dry eye or another ocular surface disease"

Sponsors & Collaborators

• Superior University: lead

Study Sites (1)

Al Mustafa eye hospital lahore

Lahore, Punjab Province, Pakistan

Location

MeSH Terms

Conditions

Conjunctivitis, Allergic

Condition Hierarchy (Ancestors)

Conjunctivitis; Conjunctival Diseases; Eye Diseases; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: March 29, 2025
• First Posted: April 6, 2025
• Study Start: March 20, 2025
• Primary Completion: June 20, 2025
• Study Completion: February 20, 2026
• Last Updated: April 6, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)