Comparison of Pain Relief After Arthroscopic Knee Surgery: Adductor Canal Block and Genicular Nerve Block

NCT06909851 | Recruiting

• 1 other identifier: BSH-ANES-SA-01
• Study Type: interventional
• Target: 68
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective randomized study aims to compare the analgesic efficacy of Adductor Canal Block (ACB) and Genicular Nerve Block (GNB) groups to relieve postoperative pain in participants between ages of 18-72 undergoing arthroscopic knee surgery under spinal anesthesia. The main question it aims to answer is: To demonstrate whether Adductor Canal Block or Genicular Nerve Block is more effective in postoperative analgesia in patients undergoing arthroscopic knee surgery based on pain scores, opioid consumption and patient satisfaction. Arthroscopic knee surgeries cause severe pain especially with movement in the post-operative period. After surgery, the movements of the participants are severely restricted because of pain, which increases the possibility of complications and postpones post-operative knee exercises. In this study, the participants' pain status, VAS score, opioid consumption and patient satisfaction will be measured with a simple scoring system for 24 hours at predetermined time points and then compared. Both types of blocks have pain-relieving effects. This study will only investigate which one is more effective in reducing pain, and there will be no deficiency in relieving the pain of the participants.

Conditions

Opioid Use; Pain Postoperative; Arthroscopic Knee Surgeries

Keywords

Genicular Nerve Block; Arthroscopic Knee Surgery; Adductor Canal Block; Postoperative Analgesia

Outcome Measures

Primary Outcomes (1)

• Effectiveness on Pain Scores (NRS)

  Postoperative pain assessment is performed using the Numerical Rating Scale (NRS). Participants are asked about their rest pain at Baseline 0, postoperative 1st, 2nd, 4th, 6th, 12th, and 24th hours after applying a preoperative peripheral nerve block. With this method, participants rate their pain with a precise numerical value from 0 to 10. While zero(0) represents "no pain"; Ten (10) represents the opposite end of the pain continuum (e.g., "The most intense pain imaginable," "As intense pain as possible," "Maximum pain").

  Postoperative 24 hours

Secondary Outcomes (7)

• Amount of rescue analgesia administration

  Postoperative 24 hours.

• Postoperative Blood pressure

  Postoperative 24 hours

• Length of hospital stay

  Postoperative 14 days

• First Time Of Mobilisation/Exercise

  Postoperative 24 hours

• The Time of Rescue Analgesic

  Postoperative 24 hours

Study Arms (2)

ACB Group

ACTIVE COMPARATOR

Participants undergoing arthroscopic knee surgery under spinal anestesia receiving pre operative Adductor Canal Block (ACB)

Procedure: Adductor Canal Block (ACB)

Genicular Nerve Block

ACTIVE COMPARATOR

Participants undergoing arthroscopic knee surgery under spinal anestesia receiving pre operative Genicular Nerve Block (GNB)

Procedure: Genicular Nerve Block (GNB)

Interventions

Adductor Canal Block (ACB) PROCEDURE

Evaluation of postoperative analgesic effectiveness of ACB block in participants undergoing arthroscopic knee surgery under spinal anesthesia.

ACB Group

Genicular Nerve Block (GNB) PROCEDURE

Evaluation of postoperative analgesic effectiveness of GNB block in participants undergoing arthroscopic knee surgery under spinal anesthesia.

Genicular Nerve Block

Eligibility Criteria

• Age: 18 Years - 72 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Voluntary willingness to participate in the study.
• Patients undergoing arthroscopic knee surgery (meniscus, ACL, arthroscopic intervention etc).
• ASA I-II-III classification.
• Aged between 18-72 years.
• No contraindications for regional anesthesia, and deemed suitable for regional anesthesia by the anesthesiologist.
• Undergoing surgery under spinal anesthesia.
• Fully oriented and able to cooperate.

You may not qualify if:

• Undergoing surgery under general anesthesia.
• Chronic analgesic use.
• Presence of an active infection at the procedure site.
• Outside the appropriate age range.
• Inability to comply with postoperative pain/NRS follow-ups.
• ASA IV-V classification.
• Non-voluntary patients.
• Pregnancy.

Sponsors & Collaborators

• Başakşehir Çam & Sakura City Hospital: lead

Study Sites (1)

Başakşehir Çam & Sakura City Hospital

Istanbul, Turkey (Türkiye)

RECRUITING

Related Publications (2)

• Vora MU, Nicholas TA, Kassel CA, Grant SA. Adductor canal block for knee surgical procedures: review article. J Clin Anesth. 2016 Dec;35:295-303. doi: 10.1016/j.jclinane.2016.08.021. Epub 2016 Oct 11.

  PMID: 27871547 BACKGROUND

• Tamam A, Guven Kose S, Kose HC, Akkaya OT. Comparison of the Effectiveness of Ultrasound-Guided Proximal, Mid, or Distal Adductor Canal Block after Knee Arthroscopy. Turk J Anaesthesiol Reanim. 2023 Apr;51(2):135-142. doi: 10.5152/TJAR.2023.22225.

  PMID: 37140579 BACKGROUND

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Central Study Contacts

MUZAFFER GENCER

CONTACT

+905059436459; dr.m.gencer07@gmail.com

SİNAN ANAŞ

CONTACT

+905314220762; tharkunbalrogs@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor Doctor

Model Details: Patients who are admitted to the orthopedic and traumatology clinic and are scheduled for arthroscopic knee surgery will be informed and monitored prior to the operation under spinal anesthesia. Preoperatively, either Adductor Canal Block (ACB) (Group A) or Genicular Nerve Block (GNB) (Group B) will be applied. Randomization will be performed using a computer-based method (http://www.randomizer.org) with a 1:1 allocation.

Study Record Dates

• First Submitted: March 21, 2025
• First Posted: April 4, 2025
• Study Start: March 10, 2025
• Primary Completion: August 31, 2025
• Study Completion: September 30, 2025
• Last Updated: April 4, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)