Airway Clearance by Fiberoptic Bronchoscopy in Bronchiectasis Followed by Gentamicin and Dexamethason Injection

NCT06906354 | Completed DMC

• 1 other identifier: bronchiectasis FOB
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Fiberoptic Bronchoscopic Removal of Secretions and Antibiotic Injection

Conditions

Bronchiectasis Adult; Bronchiectasis With Acute Exacerbation

Keywords

bronchoscopy; bronchiectasis

Outcome Measures

Primary Outcomes (1)

• Dyspnea Borg Scale

  improvement in the scale of dyspnea before and after the procedure

  one month

Study Arms (1)

fiberoptic bronchoscopy in one group

ACTIVE COMPARATOR

Airway Clearance by Fiberoptic Bronchoscopy in Bronchiectasis Followed by Gentamicin and Dexamethason Injection

Procedure: Airway Clearance by Fiberoptic Bronchoscopy in Bronchiectasis Followed by Gentamicin and Dexamethason Injection

Interventions

Airway Clearance by Fiberoptic Bronchoscopy in Bronchiectasis Followed by Gentamicin and Dexamethason Injection PROCEDURE

Airway Clearance by Fiberoptic Bronchoscopy in Bronchiectasis Followed by Gentamicin and Dexamethason Injection

fiberoptic bronchoscopy in one group

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult subjects. 2- Male and female subjects are enrolled. 3- patients with NCFB confirmed by chest high-resolution computed tomography (HRCT) 4- patients needing antibiotic treatment at the hospital due to exacerbation 5- Patients who underwent AC by bronchoscopy at the hospital.

You may not qualify if:

• Uncooperative subjects. 2- Unwilling to participate. 3- Inability to lie on the back with raised arms over the head for HRCT. 4- Presence of cystic pulmonary fibrosis; 5- Patients with active pulmonary tuberculosis; 6- Those awaiting surgery; 7- Patients who underwent interventional therapy for hemoptysis; those with allergic bronchopulmonary aspergillosis (ABPA); 8- Patients who did not undergo bronchoscopy for different reasons or combined with lung cancer.

Sponsors & Collaborators

• Alexandria University: lead

Study Sites (1)

Chest Department -Faculty of Medicine

Alexandria, Egypt, 11511, Egypt

Location

Related Links

• bronchoscopy in bronchiectasis
• fiberoptic bronchoscopy in bronchiectasis

MeSH Terms

Conditions

Bronchiectasis

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases

Study Officials

• mohamed sabry Eltarhony, lecturer

  Alexandria University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Fiberoptic Airway Clearance in Bronchiectasis Exacerbation and Gentamicin-Dexamethason Injection

Study Record Dates

• First Submitted: March 26, 2025
• First Posted: April 2, 2025
• Study Start: November 11, 2024
• Primary Completion: January 15, 2025
• Study Completion: January 20, 2025
• Last Updated: April 2, 2025

Record last verified: 2025-01

Locations

EG (1)