Resumption of Enteral Feeding After Bowel Anastomosis

NCT06906289 | Recruiting

• 1 other identifier: 806/DME/KMC
• Study Type: interventional
• Target: 204
• Locations: 1 country
• Sites: 1

Brief Summary

Resumption of oral feeding after small intestine surgery is a matter of controversy .Some surgeons advocate early resumption while others don't.early feeding is initiated as soon as the patient recovers from effects of anaesthesia, while late resumption is started after 24-48 hours after surgery.Recent studies and guidelines suggest early feeding. The aim of this study is to compare the early and late resumption of oral feeding.

Conditions

Enhanced Recovery After Surgery; Hospital Stay, Length of Stay in Hospital From Time of Surgery Till Discharge; Defecation; Vomiting, Postoperative; Anastomotic Leak; Flatus

Keywords

Enhanced Recover After Surgery; Hospital Stay; Postoperative vomiting; Anastomotic leak

Outcome Measures

Primary Outcomes (1)

• Time to passage of stool/flatus

  Time to passage of stool or flatus after surgery ,as reported by the patient or noticed by nurse.Time will be measured in day(s).

  Upto 2 weeks from surgery .From the time of surgery to passage of stool or flatus or death due to any cause, whichever comes first.

Secondary Outcomes (2)

• Hospital stay

  Upto 50 weeks postoperatively ,From surgery to discharge or death , whichever comes first.

• Vomiting

  Upto 50 weeks postoperatively ,From surgery to discharge or death , whichever comes first.

Study Arms (2)

Early group

EXPERIMENTAL

Early group includes patients in whom enteral feeding is resumed within 24 hours once fully conscious from effects of anesthesia

Other: resumption of enteral feeding within 24 hours of surgery; Other: resumption of enteral feeding after 24-48 hours

Late group

EXPERIMENTAL

Late group includes patients in whom enteral feeding is started 24-48 hours after recovery from anesthesia

Other: resumption of enteral feeding within 24 hours of surgery; Other: resumption of enteral feeding after 24-48 hours

Interventions

resumption of enteral feeding within 24 hours of surgery OTHER

Patients will be subjected to resumption of enteral feeding within 24 hours of surgery

Early group; Late group

resumption of enteral feeding after 24-48 hours OTHER

Patients will be subjected to late resumption of enteral feeding after 24 to 48 hours of surgery

Early group; Late group

Eligibility Criteria

• Age: 15 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• All patients undergoing small bowel anastomosis for any indication in elective setting
• Patients of age between 15 to 65 years.
• All genders

You may not qualify if:

• Patient using glucocorticoids or other immunosuppressive drugs
• non conseting individuals
• Patient having history of gastrectomy

Sponsors & Collaborators

• Khyber Teaching Hospital: lead

Study Sites (1)

Khyber Teaching Hospital

Peshawar, KPK, 25000, Pakistan

RECRUITING

MeSH Terms

Conditions

Postoperative Nausea and Vomiting; Anastomotic Leak; Flatulence

Interventions

Surgical Procedures, Operative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Nausea; Signs and Symptoms, Digestive; Signs and Symptoms; Vomiting

Central Study Contacts

Saeed Sarwar, MBBS

CONTACT

+92342 0973863; saeedkmc2020@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: March 19, 2025
• First Posted: April 2, 2025
• Study Start: October 1, 2024
• Primary Completion: December 1, 2025
• Study Completion: December 1, 2025
• Last Updated: April 2, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)