Transient Pseudohypoaldosteronism Affecting Children With Urinary Tract Malformation

NCT06905600 | Recruiting

• 1 other identifier: 9139
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Pseudohypoaldosteronism is a pathology affecting children under 6 months of age, little known but which can have serious consequences. There are no real figures on the prevalence of this pathology in France. The exact pathophysiology is not known and the management is not currently codified. This is why it is interesting to study this pathology and its treatment on a national scale in order to think about the best possible treatment, as well as to raise awareness of this pathology among different health professionals.

Conditions

Pseudohypoaldosteronism

Keywords

Pseudohypoaldosteronism; pseudohypoaldosteronism in children

Outcome Measures

Primary Outcomes (1)

• National comparison of clinical and therapeutic practices concerning the management of pseudohypoaldosteronism in children with urinary malformations and/or urinary infections

  This study compares clinical and therapeutic practices The retrospective analysis of the data will be carried out using classic statistical tests (Student's test, Fisher's test, ROC curve)

  Up to 1 year

Eligibility Criteria

• Age: 1 Year - 6 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Minor subjects aged less than 6 years at the time of diagnosis of pseudohypoaldosteronism in the context of urinary malformation and/or urinary infection between January 1, 2018 and December 31, 2023

You may qualify if:

• Minor subjects aged less than 6 years at the time of diagnosis
• Diagnosis of pseudohypoaldosteronism in the context of urinary malformation and/or urinary infection between January 1, 2018 and December 31, 2023
• Subject (and/or their parental authority) having not expressed, after information, their opposition to the reuse of their data for the purposes of this research.

You may not qualify if:

• Subject (or their parents) having expressed their (their) opposition to participating in the study

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service pédiatrie 1 - CHU de Strasbourg - France

Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

Pseudohypoaldosteronism

Condition Hierarchy (Ancestors)

Renal Tubular Transport, Inborn Errors; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Central Study Contacts

Ariane ZALOSZYC, MD

CONTACT

33 3 88 12 77 42; ariane.zaloszyc@chru-strasbourg.fr

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 8, 2024
• First Posted: April 1, 2025
• Study Start: January 31, 2024
• Primary Completion: December 1, 2025
• Study Completion: December 31, 2025
• Last Updated: April 1, 2025

Record last verified: 2024-07

Locations

FR (1)