NCT06901362|Completed
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Sponsor study identifier
observational
401
1 country
1
Study Start
April 1, 2025
Actual (reported)Primary Completion
August 31, 2025
Actual (reported)Study Completion
November 30, 2025
Actual (reported)This study is a cross-sectional study. The study aims to determine the levels of immunity against hepatitis B virus and varicella-zoster virus in medical students.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
November 30, 2025
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
March 22, 2025
Actual (reported)March 28, 2025
Actual (reported)April 1, 2025
Actual (reported)August 31, 2025
Actual (reported)November 30, 2025
Actual (reported)The seroprevalence of hepatitis B virus
The immunity level against the hepatitis B virus is assessed.
From enrollment to the end of treatment at 6 months
The seroprevalence of varicella-zoster virus
The immunity level against varicella-zoster virus is assessed.
From enrollment to the end of treatment at 6 months
The vaccination rate of hepatitis B virus
From enrollment to the end of treatment at 6 months
The vaccination rate of varicella-zoster virus
From enrollment to the end of treatment at 6 months
Medical students aged 18 years or older
Medical students aged 18 years or older are included.
Narongkorn Saiphoklang
Pathum Thani, Changwat Pathum Thani, 12120, Thailand
Techasathit W, Ratanasuwan W, Sonjai A, Sangsiriwut K, Anekthananon T, Suwanagool S. Vaccination against hepatitis B virus: are Thai medical students sufficiently protected? J Med Assoc Thai. 2005 Mar;88(3):329-34.
Baer G, Bonhoeffer J, Schaad UB, Heininger U. Seroprevalence and immunization history of selected vaccine preventable diseases in medical students. Vaccine. 2005 Mar 14;23(16):2016-20. doi: 10.1016/j.vaccine.2004.03.073.
Blood samples for measuring immunity levels against the hepatitis B virus and varicella-zoster virus.
Narongkorn Saiphoklang, MD
Thammasat University Faculty of Medicine
401 participants (actual enrollment reported by the registry).
First Submitted
March 22, 2025
First Posted
March 28, 2025
Study Start
April 1, 2025
Actual (reported)Contact the study team to confirm eligibility.
Balbi O, Baldi S, Rizza S, Pietroiusti A, Perrone S, Coppeta L. Seroprevalence survey for Varicella among healthcare workers and medical students in Italy. Hum Vaccin Immunother. 2021 Feb 1;17(2):372-376. doi: 10.1080/21645515.2020.1771989. Epub 2020 Jul 9.
Pourakbari B, Shahbaznezhad L, Parvaneh N, Nikkhah S, Mahmoudi S, Teymuri M, Alyari A, Mamishi S. Seroepidemiology of Varicella Zoster Virus among children, adolescents and medical students in a referral children medical center, Tehran, Iran. Iran J Microbiol. 2012 Sep;4(3):136-8.
Sheek-Hussein M, Hashmey R, Alsuwaidi AR, Al Maskari F, Amiri L, Souid AK. Seroprevalence of measles, mumps, rubella, varicella-zoster and hepatitis A-C in Emirati medical students. BMC Public Health. 2012 Dec 5;12:1047. doi: 10.1186/1471-2458-12-1047.
Cardenas-Perea ME, Gomez-Conde E, Santos-Lopez G, Perez-Contreras I, Diaz-Orea MA, Gandara-Ramirez JL, Cruz Y Lopez OR, Marquez-Dominguez L, Sosa-Jurado F. Hepatitis B surface antibodies in medical students from a public university in Puebla, Mexico. Hum Vaccin Immunother. 2016 Jul 2;12(7):1857-62. doi: 10.1080/21645515.2016.1151587. Epub 2016 May 12.
Sartorelli P, Occhialini F, Miceli R, Pietronigro A, Bianciardi L, Salini C, Messina G. The seroprevalence of the hepatitis B virus in Italian medical students after 3 decades since the introduction of universal vaccination. Int J Occup Med Environ Health. 2022 Feb 15;35(1):75-80. doi: 10.13075/ijomeh.1896.01835. Epub 2021 Aug 25.
Tesfa T, Hawulte B, Tolera A, Abate D. Hepatitis B virus infection and associated risk factors among medical students in eastern Ethiopia. PLoS One. 2021 Feb 19;16(2):e0247267. doi: 10.1371/journal.pone.0247267. eCollection 2021.
Rathi A, Kumar V, Majhi J, Jain S, Lal P, Singh S. Assessment of knowledge, attitude, and practices toward prevention of hepatitis B infection among medical students in a high-risk setting of a newly established medical institution. J Lab Physicians. 2018 Oct-Dec;10(4):374-379. doi: 10.4103/JLP.JLP_93_18.
Yoda T, Katsuyama H. Analysis of antibody-negative medical students after hepatitis B vaccination in Japan. Hum Vaccin Immunother. 2021 Mar 4;17(3):852-856. doi: 10.1080/21645515.2020.1788309. Epub 2020 Aug 5.
Bianchi FP, Tafuri S, Larocca AMV, Germinario CA, Stefanizzi P. Long -term persistence of antibodies against varicella in fully immunized healthcare workers: an Italian retrospective cohort study. BMC Infect Dis. 2021 May 25;21(1):475. doi: 10.1186/s12879-021-06180-x.
Phattraprayoon N, Kakheaw J, Soonklang K, Cheirsilpa K, Ungtrakul T, Auewarakul C, Mahanonda N. Duration of Hepatitis B Vaccine-Induced Protection among Medical Students and Healthcare Workers following Primary Vaccination in Infancy and Rate of Immunity Decline. Vaccines (Basel). 2022 Feb 10;10(2):267. doi: 10.3390/vaccines10020267.
Primary Completion
August 31, 2025
Actual (reported)Study Completion
November 30, 2025
Actual (reported)Last Updated
December 23, 2025
Record last verified: 2025-04
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