NCT06898892

Brief Summary

The goal of this clinical trial is to compare the accuracy of sonographic vs. magnetic resonance fetal weight estimation in suspected fetal macrosomia in term pregnancy. Pregnant patient at term with suspected macrosomia will participate and undergo both sonographic and magnetic resonance fetal weight estimations and the actual birthweight will be recorded and compared with the fetal weight estimations

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
22mo left

Started Feb 2025

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress41%
Feb 2025Feb 2028

Study Start

First participant enrolled

February 13, 2025

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

February 14, 2025

Completed
1 month until next milestone

First Posted

Study publicly available on registry

March 27, 2025

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 13, 2027

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

February 13, 2028

Last Updated

March 27, 2025

Status Verified

March 1, 2025

Enrollment Period

2 years

First QC Date

February 14, 2025

Last Update Submit

March 25, 2025

Conditions

Keywords

fetal weight estimation, accuracy

Outcome Measures

Primary Outcomes (1)

  • MRI fetal weight estimation accuracy

    gram

    from enollment to Performing the MRI at 1 week

Study Arms (1)

suspected macrosomia

EXPERIMENTAL

suspected macrosomia at term who will undergo sonographic and MRI fetal weight estimation

Diagnostic Test: Fetal MRI

Interventions

Fetal MRIDIAGNOSTIC_TEST

all participant will undergo MRI fetal weight estimation

suspected macrosomia

Eligibility Criteria

Age18 Years - 50 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility Detailspregnant women
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • singleton pregnancy at term, suspected fetal macrosomia,

You may not qualify if:

  • fetal anomaly multiple pregnancy PROM

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Galilee medical center

Nahariya, Israel

RECRUITING

Related Publications (3)

  • Langer O, Berkus MD, Huff RW, Samueloff A. Shoulder dystocia: should the fetus weighing greater than or equal to 4000 grams be delivered by cesarean section? Am J Obstet Gynecol. 1991 Oct;165(4 Pt 1):831-7. doi: 10.1016/0002-9378(91)90424-p.

    PMID: 1951539BACKGROUND
  • Kadji C, Cannie MM, Kang X, Carlin A, Benjou Etchoua S, Resta S, Dutemeyer V, Abi-Khalil F, Mazzone E, Bevilacqua E, Jani JC. Fetal magnetic resonance imaging at 36 weeks predicts neonatal macrosomia: the PREMACRO study. Am J Obstet Gynecol. 2022 Feb;226(2):238.e1-238.e12. doi: 10.1016/j.ajog.2021.08.001. Epub 2021 Aug 4.

    PMID: 34358479BACKGROUND
  • Malin GL, Bugg GJ, Takwoingi Y, Thornton JG, Jones NW. Antenatal magnetic resonance imaging versus ultrasound for predicting neonatal macrosomia: a systematic review and meta-analysis. BJOG. 2016 Jan;123(1):77-88. doi: 10.1111/1471-0528.13517. Epub 2015 Jul 29.

    PMID: 26224221BACKGROUND

Study Officials

  • Amal shahin

    Galilee Medical Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Maya Frank Wolf, Prof.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Head of Maternal Fetal Medicine Unit

Study Record Dates

First Submitted

February 14, 2025

First Posted

March 27, 2025

Study Start

February 13, 2025

Primary Completion (Estimated)

February 13, 2027

Study Completion (Estimated)

February 13, 2028

Last Updated

March 27, 2025

Record last verified: 2025-03

Data Sharing

IPD Sharing
Will share
Shared Documents
STUDY PROTOCOL, CSR

Locations