Outcomes of Critically Ill Patients Undergoing RRT- a Registry Based Study.

NCT06897254 | Completed

• 1 other identifier: 518(6-11)E2-079/080
• Study Type: observational
• Target: 516
• Locations: 1 country
• Sites: 1

Brief Summary

Rationale: Acute kidney injury (AKI) requiring renal replacement therapy (RRT) is a frequently occurring entity among critically ill patients. This study aims to determine the outcomes of patients undergoing renal replacement therapy in the ICU. Study Objective: To find the outcomes of patients undergoing RRT in the ICU in terms of mortality and length of ICU stay. Design: A registry based, retrospective, descriptive study. Sample size: Convenience sampling of all the patients who require RRT during the ICU stay. Duration: Retrospective data from three years January 1, 2020 to December 30, 2023. Place: Intensive care units (ICUs) of the Department of Critical Care Medicine, Tribhuvan University Teaching Hospital (TUTH). Interventions: Not applicable Expected results: The study will help determine the outcomes of the critically ill patients undergoing RRT in a low middle income country ICU.

Conditions

Renal Replacement Therapies; Outcome Assessment

Keywords

renal replacement therapy; hemodialysis; intensive care unit; outcomes

Outcome Measures

Primary Outcomes (1)

• ICU mortality

  A the end of 3 years

Secondary Outcomes (1)

• Treatment limitations

  At the end of 3 years

Other Outcomes (1)

• LOS-ICU

  At the end of 3 years

Study Arms (2)

RRT

Patients undergoing renal replacement therapy

NRRT

Patients not undergoing renal replacement therapy

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients admitted to the ICU requiring renal replacement therapy

You may qualify if:

• Age\>18 years
• Admission to the ICU
• All patients undergoing RRT during ICU stay

You may not qualify if:

• None

Sponsors & Collaborators

• Tribhuvan University Teaching Hospital, Institute Of Medicine.: lead

Study Sites (1)

Tribhuvan University Teaching Hospital

Mahārājgañj, Bagmati, 44600, Nepal

Location

Related Publications (2)

• Cerda J, Mohan S, Garcia-Garcia G, Jha V, Samavedam S, Gowrishankar S, Bagga A, Chakravarthi R, Mehta R. Acute Kidney Injury Recognition in Low- and Middle-Income Countries. Kidney Int Rep. 2017 Jul;2(4):530-543. doi: 10.1016/j.ekir.2017.04.009. Epub 2017 Apr 25.

  PMID: 29034358 BACKGROUND

• Andonovic M, Traynor JP, Shaw M, Sim MAB, Mark PB, Puxty KA. Short- and long-term outcomes of intensive care patients with acute kidney disease. EClinicalMedicine. 2022 Feb 12;44:101291. doi: 10.1016/j.eclinm.2022.101291. eCollection 2022 Feb.

  PMID: 35198917 BACKGROUND

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Primary investigator

Study Record Dates

• First Submitted: March 16, 2025
• First Posted: March 26, 2025
• Study Start: January 1, 2020
• Primary Completion: December 31, 2022
• Study Completion: December 31, 2022
• Last Updated: April 16, 2025

Record last verified: 2025-04

Locations

NE (1)