The Impact of Functional Exercise Training on Postoperative Knee Joint Recovery in Patients with Meniscal Injury

NCT06894706 | Completed

• 1 other identifier: No. 20240927
• Study Type: interventional
• Target: 96
• Locations: 1 country
• Sites: 1

Brief Summary

AIM: To investigate the impact of functional exercise training on postoperative functional recovery in patients with knee meniscus injuries. METHODS:A prospective randomized controlled trial (RCT) was conducted from April 2023 to September 2024, involving 96 patients with knee meniscus injuries who underwent meniscus repair interventions. Participants were randomly assigned to either the Control （CON） group (n=48) or the functional exercise training (FET) group (n=48) using a computer-generated random number table. The CON group received standard rehabilitation, while the FET group underwent functional exercise training. Clinical outcomes were evaluated at baseline, 1 month, and 6 months post-intervention, including the Lysholm score, IKDC score, VAS pain score, range of motion (ROM), serum levels of prostaglandin E2 (PGE2) and serotonin (5-HT), as well as passive 60° position sense and 60° motion sense. Postoperative complications occurring within 1 month were also recorded.

Conditions

Functional Exercise Training; Knee Meniscus Injury; Knee Joint Function

Keywords

Functional exercise training; knee meniscus injury; knee joint function

Outcome Measures

Primary Outcomes (1)

• Demographic data comparison

  baseline, pre-intervention

Secondary Outcomes (9)

• Lysholm Knee Scoring Scale scores

  up to 24 weeks

• International Society of Knee Injuries and Arthroscopy Score

  up to 24 weeks

• Range of Motion

  up to 24 weeks

• Visual Analog Scale

  up to 24 weeks

• Passive position sense

  up to 24 weeks

Study Arms (2)

Control （CON） group

OTHER

Both groups were given arthroscopy and meniscoplasty. After operation, the control group received active knee flexion and extension exercise, ankle pump training, quadriceps muscle training and other routine rehabilitation training.

Behavioral: Control （CON） group

Functional exercise training (FET) group

OTHER

Patients in the observation group were supplemented with neuromuscular training on the basis of routine rehabilitation training, and received rehabilitation education before training. The patients were informed of the specific content, frequency, expected effect and importance of training in various forms such as on-site demonstration combined with publicity brochures and playing videos, so as to improve patient cooperation.

Behavioral: Functional exercise training (FET) group

Interventions

Control （CON） group BEHAVIORAL

Both groups were given arthroscopy and meniscoplasty. After operation, the control group received active knee flexion and extension exercise, ankle pump training, quadriceps muscle training and other routine rehabilitation training.

Control （CON） group

Functional exercise training (FET) group BEHAVIORAL

Patients in the observation group were supplemented with neuromuscular training on the basis of routine rehabilitation training, and received rehabilitation education before training. The patients were informed of the specific content, frequency, expected effect and importance of training in various forms such as on-site demonstration combined with publicity brochures and playing videos, so as to improve patient cooperation.

Functional exercise training (FET) group

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• meniscus injury was diagnosed by magnetic resonance imaging; meniscoplasty was performed; No shedding occurred during follow-up.

You may not qualify if:

• Patients with joint dislocation and fracture; poor compliance; severe osteoarthritis, rheumatoid arthritis; Combined with metabolic diseases, coagulation disorders and serious organic diseases.

Sponsors & Collaborators

• Biao Yang: lead

Study Sites (1)

Lanzhou Anning District People's Hospital

Lanzhou, China

Location

MeSH Terms

Interventions

Population Groups

Intervention Hierarchy (Ancestors)

Demography; Population Characteristics

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Lanzhou Anning District People's Hospital

Study Record Dates

• First Submitted: March 10, 2025
• First Posted: March 25, 2025
• Study Start: April 1, 2023
• Primary Completion: September 1, 2024
• Study Completion: December 1, 2024
• Last Updated: March 25, 2025

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)