Cervical Myelopathy in Hip Fracture Patients

NCT06893406 | Recruiting

• 1 other identifier: 24990
• Study Type: interventional
• Target: 75
• Locations: 1 country
• Sites: 3

Brief Summary

Recent evidence has demonstrated a high rate of undiagnosed cervical myelopathy in patients presenting with hip fractures from a ground level fall. Identification and treatment of cervical myelopathy can help prevent falls and future fragility fractures. The purpose of this study is to screen ground level fall hip fracture patients for cervical myelopathy using a history, physical exam, and then offer an MRI if indicated.

Conditions

Cervical Myelopathy; Hip Fractures

Keywords

Hip fracture; Cervical myelopathy

Outcome Measures

Primary Outcomes (2)

• Detection of cervical myelopathy on history and physical exam

  The number of hip fracture participants whose history and physical exam positively demonstrate signs or symptoms of cervical myelopathy will be compared to the number of hip fracture participants whose history and physical exam do not demonstrate signs or symptoms of cervical myelopathy.

  Once, at time of enrollment

• Diagnosis of cervical myelopathy on cervical MRI

  Hip fracture participants whose history and physical exam positively demonstrate signs or symptoms of cervical myelopathy will be referred for a cervical MRI, to occur prior to hospital discharge. The number of participants whose cervical MRI confirms this diagnosis will be compared to the number of participants for whom cervical MRI does not confirm this diagnosis.

  Once, prior to hospital discharge

Study Arms (1)

Evaluation for Cervical Myelopathy

EXPERIMENTAL

Hip fracture patients who agree to participate will undergo a history and physical exam to specifically evaluate for clinical signs or symptoms of cervical myelopathy. If the history and physical exam is positive for such symptoms, a cervical MRI will be scheduled as part of standard care to further evaluate for this diagnosis. If the history and physical exam is negative for such symptoms, further clinical evaluation for this condition will not occur.

Diagnostic Test: Cervical MRI; Other: History & Physical Exam

Interventions

Cervical MRI DIAGNOSTIC_TEST

Participants whose history and physical exam indicate signs or symptoms of cervical myelopathy will be scheduled for a cervical MRI.

Evaluation for Cervical Myelopathy

History & Physical Exam OTHER

A history and physical exam to evaluate for specific signs and symptoms of cervical myelopathy will be performed.

Evaluation for Cervical Myelopathy

Eligibility Criteria

• Age: 50 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patient admitted to Eskenazi, Methodist, or IU North hospital for a hip fracture (femoral neck, intertrochanteric, subtrochanteric, or pertrochanteric fracture) that was caused by a ground level fall.

You may not qualify if:

• Neurologic or cognitive disorder explaining the fall (dementia, Parkinson's disease, delirium, etc.)
• Syncopal fall or fall caused by stroke or a heart condition

Sponsors & Collaborators

• Indiana University: lead

Study Sites (3)

Indiana University North Hospital

Fishers, Indiana, 46032, United States

RECRUITING

Eskenazi Hospital

Indianapolis, Indiana, 46202, United States

RECRUITING

Indiana University Health Methodist Hospital

Indianapolis, Indiana, 46202, United States

RECRUITING

Related Publications (1)

• Radcliff KE, Curry EP, Trimba R, Walker JB, Purtill JJ, Austin MS, Parvizi J, Vaccaro AR, Hilibrand AS, Albert TJ. High Incidence of Undiagnosed Cervical Myelopathy in Patients With Hip Fracture Compared With Controls. J Orthop Trauma. 2016 Apr;30(4):189-93. doi: 10.1097/BOT.0000000000000485.

  PMID: 26562581 BACKGROUND

MeSH Terms

Conditions

Hip Fractures

Interventions

Health Records, Personal; Restraint, Physical

Condition Hierarchy (Ancestors)

Femoral Fractures; Fractures, Bone; Wounds and Injuries; Hip Injuries; Leg Injuries

Intervention Hierarchy (Ancestors)

Medical Records; Records; Data Collection; Epidemiologic Methods; Investigative Techniques; Behavior Control; Therapeutics; Immobilization

Central Study Contacts

Zachary J Gunderson, MD

CONTACT

2193215850; zgunders@iu.edu

Rowan Flynn, MD

CONTACT

8082641713

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SEQUENTIAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Clinical Neurological Surgery

Model Details: All hip fracture patients that provide consent for participation will undergo a history and physical examination to specifically evaluate for potential cervical myelopathy. If the history and physical exam detect signs or symptoms of cervical myelopathy, a cervical MRI will be scheduled to confirm the diagnosis.

Study Record Dates

• First Submitted: March 18, 2025
• First Posted: March 25, 2025
• Study Start: May 1, 2025
• Primary Completion: March 20, 2026
• Study Completion: March 20, 2026
• Last Updated: October 31, 2025

Record last verified: 2025-10

Data Sharing

• IPD Sharing: Will not share

Locations

US (3)