Bacteriological Profile and Antibiotic Sensitivity in Neonatal Intensive Care Unit At Assuit University Children Hospital

NCT06891768 | Not Yet Recruiting

• 1 other identifier: Ab sensitivity in neonates
• Study Type: observational
• Target: 134
• Locations: 0 countries
• Sites: N/A

Brief Summary

The study aims to assess the bacteriological profile and antibiotic sensitivity in NICU of pediatric hospital of assuit university.

Conditions

Nosocomial Infection in Neonatal Intensive Care Unit

Outcome Measures

Primary Outcomes (1)

• Bacteriological profile and antibiotic sensitivity of the nosocomial infection in neonatal intensive care unit at Assuit University Children hospital

  Baseline

Interventions

Blood culture DIAGNOSTIC_TEST

Blood culture for bacteriological profile and antibiotic sensitivity

Eligibility Criteria

• Age: 2 Days - 28 Days
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

Neonates that suspected to have nosocomial infection in neonatal intensive care unit at Assuit University Children hospital

You may qualify if:

• Neonates \<28 days of life .
• Hospital stay \>48 h .
• Neonates without signs of sepsis at time of admission .
• Accepted to participate in this study .

You may not qualify if:

• Neonates \>28 days of life .
• Hospital stay \<48 h .
• Neonates with neonatal sepsis at time of admission.
• Refused to participate in this study .

Sponsors & Collaborators

• Assiut University: lead

Related Publications (8)

• Fahim NAE. Prevalence and antimicrobial susceptibility profile of multidrug-resistant bacteria among intensive care units patients at Ain Shams University Hospitals in Egypt-a retrospective study. J Egypt Public Health Assoc. 2021 Mar 29;96(1):7. doi: 10.1186/s42506-020-00065-8.

  PMID: 33779849 BACKGROUND

• 7. Mahmoud Mohammed GSED, Shoriet AH, Abdel-Aziz SM. Incidence and risk factors of health-care-associated infection in the neonatal intensive care unit of Assiut University Children's Hospital. Journal of Current Medical Research and Practice. 2021;6(1):48-53.

  BACKGROUND

• 6. Salem GA. Bacterial contamination in neonatal intensive care units in Misurata, Libya: analysis of causative organisms, biofilm formation, and antimicrobial susceptibility. European Journal of Microbiology and Infectious Diseases. 2024;1(2):66-

  BACKGROUND

• Silva ACBE, Anchieta LM, Rosado V, Ferreira J, Clemente WT, Coelho JS, Mourao PHO, Romanelli RMC. Antimicrobial use for treatment of healthcare-associated infections and bacterial resistance in a reference neonatal unit. J Pediatr (Rio J). 2021 May-Jun;97(3):329-334. doi: 10.1016/j.jped.2020.06.001. Epub 2020 Jun 24.

  PMID: 32592659 BACKGROUND

• 4. Koech CC, Rono SJ, Ngeiywa MM, Jeruto P. Neonatal Factors Predisposing Neonates to Nosocomial Infections at Moi Teaching and Referral Hospital. International Journal of Education, Science and Social Sciences. 2024;3(2):35-43.

  BACKGROUND

• 3. Shwetabh R, Upadhyay MR, Upadhyay R. Aetiological Agents in Neonatal Nosocomial Sepsis and their Sensitivity Pattern from a Tertiary Care Hospital, Odisha, India: A Crosssectional Study. Seizure. 2022;6:6.

  BACKGROUND

• 2. Moses SS, Kuruvilla TS, Praveen B. Clinicomicrobiological profile of healthcare associated infections in a neonatal intensive care unit and its relation with environmental surveillance. Panacea Journal of Medical Sciences. 2023;13(1):36-41 .

  BACKGROUND

• 1. Hogeveen M, Heijting I, Jansen S, de Boode W, Hopman J, Overbeek MGD, et al. Nosocomial infections in neonatal care: a scoping review protocol of published surveillance case definitions. 2021.

  BACKGROUND

MeSH Terms

Interventions

Blood Culture

Intervention Hierarchy (Ancestors)

Microbiological Techniques; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Investigative Techniques

Study Officials

• Zeinab Mohamed Mohey, Professor of pediatrics

  Assiut University

  PRINCIPAL INVESTIGATOR

• Safwat Mohamed Abdel_Aziz, Assistant professor of pediatr

  Assiut University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Madleen Thabet Hofni

CONTACT

01274437087; madlithabet@yahoo.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: March 18, 2025
• First Posted: March 24, 2025
• Study Start: May 1, 2025
• Primary Completion: May 1, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: March 25, 2025

Record last verified: 2025-03