NCT06891092

Brief Summary

Comparison of the outcomes of bilateral implantation of extended depth of vision (EDOF) intraocular lenses (IOLs): the Rayone EMV and the Vivinex Impress XY1-EM in patients with cataract

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
25mo left

Started Jan 2026

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress14%
Jan 2026Jun 2028

First Submitted

Initial submission to the registry

March 17, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 24, 2025

Completed
9 months until next milestone

Study Start

First participant enrolled

January 1, 2026

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2027

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2028

Last Updated

January 20, 2026

Status Verified

January 1, 2026

Enrollment Period

1.4 years

First QC Date

March 17, 2025

Last Update Submit

January 15, 2026

Conditions

Keywords

non-diffractive monofocal IOLEDOFcataract

Outcome Measures

Primary Outcomes (1)

  • Visual acuity at intermediate distance

    The visual acuity at the intermediate distance will be measured using ETDRS charts at a distance of 80 centimetres and compared between the two different IOLs. The higer the number the better outcome.

    3 months

Secondary Outcomes (3)

  • Visual acuity at far distance

    3 months

  • Visual acuity at near distance

    3 months

  • Change from baseline in the quality of life

    3 months

Study Arms (2)

Rayone EMV

EXPERIMENTAL

Patient will receive the non-diffractive monofocal IOL during cataract surgery

Device: RayOne EMV

Vivinex Impress XY1-EM

EXPERIMENTAL

Patient will receive the non-diffractive monofocal IOL during cataract surgery

Device: Vivinex Impress

Interventions

non-diffractive monofocal IOL

Rayone EMV

non-diffractive monofocal IOL

Vivinex Impress XY1-EM

Eligibility Criteria

Age21 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age-related bilateral cataract
  • age 21 or older
  • visual acuity \> 0.05
  • axial length: 22.0 - 26.0 mm
  • normal findings in the medical history and physical examination unless the investigator considers an abnormality to be clinically irrelevant
  • written informed consent prior to surgery

You may not qualify if:

  • active ocular disease (e.g. chronic severe uveitis, proliferative diabetic retinopathy, chronic glaucoma not responsive to medication)
  • relevant other ophthalmic diseases such as pseudoexfoliation syndrome (PEX), intraoperative floppy iris syndrome (IFIS)
  • corneal decompensation or corneal endothelial cell insufficiency
  • previous ocular surgery or trauma
  • persons who are pregnant or nursing (pregnancy test will be taken in women of reproductive age)
  • corneal astigmatism \> 1 dpt.
  • retinopathies

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Medical University of Bialystok

Bialystok, Polska, 15-866, Poland

RECRUITING

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Central Study Contacts

Joanna Konopinska, Associate proffesor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Parallel Assignment
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 17, 2025

First Posted

March 24, 2025

Study Start

January 1, 2026

Primary Completion (Estimated)

June 1, 2027

Study Completion (Estimated)

June 1, 2028

Last Updated

January 20, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will share

De-identified participant data that underlie the results reported in this study will be available upon reasonable request for academic and non-commercial purposes beginning with results publication and ending 5 years thereafter. Proposals should be submitted to main investigator.

Shared Documents
STUDY PROTOCOL, SAP, ICF

Locations