Optical Coherence Tomography in Retinal Vein Occlusion

NCT06886893 | Not Yet Recruiting

• 1 other identifier: OCT in retinal vein occlusion
• Study Type: observational
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to evaluate how optical coherence tomography (OCT) can help predict outcomes in patients with retinal vein occlusion (RVO), a condition that affects blood flow in the retina. RVO can cause macular edema, which is swelling in the part of the eye responsible for central vision. The study will use OCT scans to assess changes in the retina and how these changes relate to vision improvement over time.

Conditions

Optical Coherence Tomography (OCT)

Keywords

OCT; retinal vein occlusion

Outcome Measures

Primary Outcomes (1)

• changes in OCT biomarkers and visual acuity post-treatment.

  Correlation between baseline OCT biomarkers and visual acuity at presentation after 1, 3, and 6 months post-treatment.

  6 months

Study Arms (1)

Adults with branch or central RVO, macular edema confirmed by OCT, and no prior RVO in the affected

Adults aged 18 years or older. Patients diagnosed with branch or central retinal vein occlusion. Patients with macular edema confirmed by OCT due to vein occlusion. Patients with no prior history of RVO in the affected eye.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

patients with retinal vein occlusion (RVO), a condition that affects blood flow in the retina. RVO can cause macular edema, which is swelling in the part of the eye responsible for central vision. Adults aged 18 or older with branch or central retinal vein occlusion. Patients must have macular edema confirmed by OCT and no previous RVO in the affected eye.

You may qualify if:

• Adults aged 18 years or older.
• Patients diagnosed with branch or central retinal vein occlusion.
• Patients with macular edema confirmed by OCT due to vein occlusion.
• Patients with no prior history of RVO in the affected eye.

You may not qualify if:

• Presence of other retinal diseases that could affect OCT interpretation (e.g., diabetic retinopathy, age-related macular degeneration).
• History of intraocular surgery within the last three months.
• Presence of significant media opacities (e.g., dense cataract, vitreous hemorrhage) that interfere with OCT imaging.

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Retinal Vein Occlusion

Condition Hierarchy (Ancestors)

Retinal Diseases; Eye Diseases; Venous Thrombosis; Thrombosis; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident at the ophtalmology department

Study Record Dates

• First Submitted: March 15, 2025
• First Posted: March 20, 2025
• Study Start: May 1, 2025
• Primary Completion: October 30, 2025
• Study Completion (Estimated): December 30, 2026
• Last Updated: March 20, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share