Diagnosis, Treatment, and Prevention of Colorectal Cancer Amid Abnormal Lipid Metabolism
The Establishment of a Diagnosis, Treatment, and Prevention System for Colorectal Cancer Under the Background of Abnormal Lipid Metabolism in Digitalization
1 other identifier
observational
1,000
0 countries
N/A
Brief Summary
This research project investigates the interplay between lipid metabolism, inflammation, and colorectal cancer (CRC). We are building a comprehensive database of CRC patients, incorporating clinical data, body composition measurements, imaging findings, and biomarkers related to lipid metabolism and inflammation. Our goal is to identify how these factors contribute to CRC development, progression, and perioperative outcomes. Ultimately, we aim to develop a digital, personalized "three-tier prevention" strategy encompassing early risk prediction, targeted interventions, and comprehensive rehabilitation for improved CRC patient care.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2017
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2017
CompletedFirst Submitted
Initial submission to the registry
March 3, 2025
CompletedFirst Posted
Study publicly available on registry
March 20, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2028
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 31, 2028
March 20, 2025
March 1, 2025
12 years
March 3, 2025
March 19, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Abdominal CT L3 level adipose tissue surface
Abdominal CT L3 level adipose tissue surface
Preoperatively
Abdominal CT L3 level skeletal muscle surface
Preoperatively
Secondary Outcomes (7)
Tumor TNM stage
immediately after the procedure
Overall Survival
3 years
Disease Free Survival
3 years
Hand grip strength
Preoperatively; Postoperatively Day 1,3,5,7
Waist Circumference
Preoperatively
- +2 more secondary outcomes
Study Arms (1)
Observation
Colorectal cancer patients after surgery
Interventions
Eligibility Criteria
Age 20-80 years, confirmed CRC diagnosis
You may qualify if:
- Age 20-80 years, confirmed CRC diagnosis, consent to participate in the study.
You may not qualify if:
- Age \<20 or \>80 years; inability to perform activities of daily living; presence of infectious diseases; lack of communication and cognitive abilities; refusal to participate in the study.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Biospecimen
Serum; Adipose Tissue; Tumor tissue; Skeletal Muscle tissue
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jing Xu, PhD
Tianjin Union Medical Center
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- OTHER
- Target Duration
- 3 Years
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Chief Physician
Study Record Dates
First Submitted
March 3, 2025
First Posted
March 20, 2025
Study Start
January 1, 2017
Primary Completion (Estimated)
December 31, 2028
Study Completion (Estimated)
December 31, 2028
Last Updated
March 20, 2025
Record last verified: 2025-03
Data Sharing
- IPD Sharing
- Will not share