The Effects of Home-based Graded Repetitive Arm Supplementary Program Group on Stroke.
1 other identifier
interventional
52
1 country
1
Brief Summary
Graded repetitive arm supplementary program (GRASP) is a self administrated, home-based rehabilitation program and has been incorporated in Canadian Stroke Best Practice Recommendations. Past studies indicated that the home-based GRASP program could facilitate the motor function and motor recovery and prevent learned nonuse of affected upper limb of stroke patients. There is lacking of research and application of the home-based GRASP program in Taiwan. Therefore, this study aims to explore the effects of the home-based GRASP program, which is mainly executed in the form of group intervention, on the affected upper limb of stroke patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable stroke
Started Mar 2025
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 12, 2025
CompletedStudy Start
First participant enrolled
March 17, 2025
CompletedFirst Posted
Study publicly available on registry
March 19, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 31, 2026
May 18, 2026
May 1, 2026
1.8 years
March 12, 2025
May 15, 2026
Conditions
Outcome Measures
Primary Outcomes (3)
Fugl-Meyer Assessment for upper extremity (FMA-UE)
The Fugl-Meyer Assessment for upper extremity (FMA-UE) includes 33 items for the motor recovery of upper limb. Each item is a 3 point ordinal scale. The total score ranges from 0 to 66, higher score means better motor recovery.
From enrollment to the end of treatment at 6 weeks
Jamar Hydraulic Hand Dynamometer (Jamar Dynamometer)
The Jamar Hydraulic Hand Dynamometer (Jamar Dynamometer) is a tool used for assessing the strength of grip, lateral pinch, and palmar pinch. The muscle strength is recorded in kilograms or pounds.
From enrollment to the end of treatment at 6 weeks
Action Research Arm Test (ARAT)
The Action Research Arm Test (ARAT) is developed for measuring the motor function of affected upper limb after stroke. ARAT includes subscales of grasp, grip, pinch, and gross movement. The total score ranges from 0 to 57, higher score means better motor function.
From enrollment to the end of treatment at 6 weeks
Secondary Outcomes (3)
Chedoke Arm and Hand Activity Inventory (CAHAI)
From enrollment to the end of treatment at 6 weeks
Rating of Everyday Arm-use in the Community and Home Scale (REACH-Scale)
From enrollment to the end of treatment at 6 weeks
Stroke Impact Scale Version 3.0 (SIS 3.0)
From enrollment to the end of treatment at 6 weeks
Study Arms (2)
GRASP group
EXPERIMENTALControl group
NO INTERVENTIONInterventions
Graded repetitive arm supplementary program (GRASP) is a self administrated, home-based rehabilitation program. home-based GRASP program could facilitate the motor function and motor recovery and prevent learned nonuse of affected upper limb of stroke patients. Participants in experimental group will receive Home GRASP program which will be executed 1hour at home per day. In addition, Participants will be requested to return hospital for follow-up and adjusting the training program in group discussion 3 times per week, lasting 4-6 weeks, and totally 12-18 sessions.
Eligibility Criteria
You may qualify if:
- Age is above 20 years old.
- Onset of first stroke complicated with hemiplegia or hemiparesis.
- The affected upper limb remains partially voluntary movements including lifting to chest level and holding for five seconds; slight flexion and extension of wrist and hand.
- Understanding and complying with two-steps commands.
- Understanding the content of trial and willing to sign informed consent.
You may not qualify if:
- Complicating with other neurological disease.
- Having Orthopedic diseases affecting the movements of upper limbs.
- Having symptoms of pain to affect the movements of upper limbs.
- Unstable vital sign or medical condition.
- Participating another rehabilitative or drug research meanwhile.
- Receiving botulinum toxin injection within three months.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Taiwan University Hospital Hsin-Chu Branch
Hsinchu, 300, Taiwan
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Chia-Yi Lin
Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital Hsin-Chu Branch
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 12, 2025
First Posted
March 19, 2025
Study Start
March 17, 2025
Primary Completion (Estimated)
December 31, 2026
Study Completion (Estimated)
December 31, 2026
Last Updated
May 18, 2026
Record last verified: 2026-05
Data Sharing
- IPD Sharing
- Will not share