NCT06883058

Brief Summary

This pilot aims to prepare the PI to receive hands-on experience in implementation and dissemination and design and lead pilot studies in palliative care. The catchment area communities experience lower cancer health outcomes and are more likely to be diagnosed with advanced cancer when compared to other surrounding areas. The PI's catchment area experiences advanced cancer, and their caregivers are at an increased risk for unmet psychosocial needs; this pre-pilot will allow the PI to focus on this critical gap in equal healthcare. The research goal of this proposal is to refine and pre-pilot an intervention titled Caregivers Patients Support to Cope with Advanced Cancer (CASA), a five-session, 60-minute telehealth series for patient-caregiver dyads. The rationale for this project is that it will lay the groundwork for a Randomized Control Trial (RCT) testing the efficacy of CASA. It will also assess the implementation of an innovative method to deliver the CASA intervention. This study aims to use the collaborative intervention planning framework and ORBIT model to modify and assess the feasibility and preliminary effect of the CASA intervention. The overall impact of this study is to improve access to psychosocial, culturally adapted interventions in the proposed catchment area.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
1mo left

Started Jul 2027

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 12, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 19, 2025

Completed
2.3 years until next milestone

Study Start

First participant enrolled

July 1, 2027

Expected
29 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 30, 2027

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 30, 2027

Last Updated

April 24, 2026

Status Verified

April 1, 2026

Enrollment Period

29 days

First QC Date

March 12, 2025

Last Update Submit

April 21, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • FACIT-Sp

    The FACIT-Sp-12 is a 12-item measure of spiritual well-being designed for individuals with cancer and other chronic illnesses. Item development was informed by input from cancer patients, psychotherapists, and religious/spiritual experts. The measure will be administered before and after the intervention.

    5 minutes

Secondary Outcomes (2)

  • PHQ-9

    5 minutes

  • GAD-7

    5 minutes

Study Arms (2)

Usual Care

PLACEBO COMPARATOR

Usual care will be provided to participants in the control group. The usual care consists of symptom management once a week and 5 sessions.

Behavioral: Placebo

CASA

EXPERIMENTAL

The Caregivers-Patients Support Intervention for Advanced Cancer (CASA) will be delivered to patients and caregivers. The sessions follow a protocol and will be held weekly or bi-weekly for a total of 5 sessions.

Behavioral: Caregivers-patients support intervention for advanced cancer (CASA)

Interventions

The Caregivers-Patients Support Intervention for Advanced Cancer (CASA) will be delivered to patients and caregivers. The sessions follow a protocol and will be held weekly or bi-weekly for a total of 5 sessions.

CASA
PlaceboBEHAVIORAL

Usual care will be provided to participants in the control group. The usual care consists of symptom management once a week and 5 sessions.

Usual Care

Eligibility Criteria

Age21 Years - 105 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Cancer patients must be stage III and IV solid tumor patients who report distress \>4 on the Distress Thermometer
  • Caregivers. Identified caregivers by distressed patients.

You may not qualify if:

  • diagnosed with a major disabling medical or psychiatric condition
  • unable to understand the consent procedure, or (3) too ill to participate, all as reported by the participant and/or determined by the investigator's judgment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ponce Research Institute

Ponce, PR, 00717, Puerto Rico

Location

MeSH Terms

Conditions

Neoplasms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 12, 2025

First Posted

March 19, 2025

Study Start (Estimated)

July 1, 2027

Primary Completion (Estimated)

July 30, 2027

Study Completion (Estimated)

July 30, 2027

Last Updated

April 24, 2026

Record last verified: 2026-04

Locations