NCT06882577

Brief Summary

Heart Evaluation of Acute ischemic stroke with Reperfusion Therapy (HEART) is a single-center observational registry evaluating the heart of patients hospitalized for acute ischemic stroke with reperfusion therapy. This registry aims to establish quantified risk stratification and prognostic models, as well as suggest effective diagnostic and therapeutic strategies.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
400

participants targeted

Target at P75+ for all trials

Timeline
36mo left

Started Mar 2025

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress28%
Mar 2025Mar 2029

First Submitted

Initial submission to the registry

March 10, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

March 18, 2025

Completed
13 days until next milestone

Study Start

First participant enrolled

March 31, 2025

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2026

Completed
3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2029

Expected
Last Updated

May 13, 2025

Status Verified

March 1, 2025

Enrollment Period

1 year

First QC Date

March 10, 2025

Last Update Submit

May 12, 2025

Conditions

Keywords

Acute ischemic strokeheartReperfusion Therapy

Outcome Measures

Primary Outcomes (1)

  • Rate of Major Adverse Cardiovascular Events

    cardiovascular mortality (any mortality due to ischemic stroke, myocardial infarction, other cardiac diseases, or unobserved sudden death), ischemic stroke, myocardial infarction and unstable angina

    1 year

Secondary Outcomes (11)

  • Rate of Major Adverse Cardiovascular Events

    90 days

  • Functional Outcome

    90 days

  • Rate of Ischemic Stroke

    1 year

  • Rate of Acute Coronary Syndrome

    1 year

  • Rate of Cardiovascular Mortality

    1 year

  • +6 more secondary outcomes

Study Arms (1)

Heart Evaluation of Acute ischemic stroke with Reperfusion Therapy

Acute ischemic stroke within 24 h after onset of stroke-related symptoms.

Other: observational only- no intervention

Interventions

observational only- no intervention

Heart Evaluation of Acute ischemic stroke with Reperfusion Therapy

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Acute ischemic stroke patients within 24 h after onset of stroke-related symptoms.

You may qualify if:

  • Written informed consent by patient
  • Age ≥ 18 years
  • Acute ischemic stroke (with matching brain lesion on MR imaging)
  • Enrolment within 24 h after onset of stroke-related symptoms.

You may not qualify if:

  • Pregnancy and / or breast-feeding.
  • Participation in an interventional study.
  • Patients refuse to participate in the research.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The first affiliated hospital of soochow university

Suzhou, Jiangsu, 215000, China

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

anticoagulant peripheral blood, serum

MeSH Terms

Conditions

Ischemic Stroke

Condition Hierarchy (Ancestors)

StrokeCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Central Study Contacts

Jianqiang Ni, MD, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
12 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical Professor

Study Record Dates

First Submitted

March 10, 2025

First Posted

March 18, 2025

Study Start

March 31, 2025

Primary Completion

March 31, 2026

Study Completion (Estimated)

March 31, 2029

Last Updated

May 13, 2025

Record last verified: 2025-03

Locations