NCT06882304

Brief Summary

The aim of the study is to measure prevalence of enamel white spot lesions in enamel in young adults after orthodontic treatment.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
368

participants targeted

Target at P75+ for all trials

Timeline
17mo left

Started Aug 2025

Typical duration for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress35%
Aug 2025Oct 2027

First Submitted

Initial submission to the registry

March 12, 2025

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 18, 2025

Completed
5 months until next milestone

Study Start

First participant enrolled

August 1, 2025

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2026

Expected
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2027

Last Updated

March 18, 2025

Status Verified

March 1, 2025

Enrollment Period

1.1 years

First QC Date

March 12, 2025

Last Update Submit

March 12, 2025

Conditions

White Spot Lesion

Outcome Measures

Primary Outcomes (1)

  • Prevalence of white spot lesions in enamel after orthodontic treatment in young adults

    to measure the prevalence of enamel white spot lesions in enamel in young adults after orthodontic treatment.

    baseline

Interventions

orthodontic treatmentOTHER

young adult after orthodontic treatment

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

1. Patients whose age between 18-30 years old consulting in the outpatient clinic. 2. Provide informed consent. 3. Co-operative patients approving to participate in the trial. 4. Both sexes are included 5. Egyptian

You may qualify if:

  • Patients whose age between 18-30 years old consulting in the outpatient clinic.
  • Provide informed consent.
  • Co-operative patients approving to participate in the trial.
  • Both sexes are included
  • Egyptian -

You may not qualify if:

  • Patients under or over this age group.
  • Patients with other developmental defect, such as; fluorosis, amelogenesis imperfecta and syndromes associated with enamel formation defects.
  • Patient with MIH .
  • Refuse to participate in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (2)

  • Tufekci E, Dixon JS, Gunsolley JC, Lindauer SJ. Prevalence of white spot lesions during orthodontic treatment with fixed appliances. Angle Orthod. 2011 Mar;81(2):206-10. doi: 10.2319/051710-262.1.

    PMID: 21208070BACKGROUND

  • Akin M, Tezcan M, Ileri Z, Ayhan F. Incidence of white spot lesions among patients treated with self- and conventional ligation systems. Clin Oral Investig. 2015 Jul;19(6):1501-6. doi: 10.1007/s00784-014-1382-3. Epub 2014 Dec 13.

    PMID: 25502686BACKGROUND

MeSH Terms

Interventions

Orthodontics

Intervention Hierarchy (Ancestors)

Dentistry

Central Study Contacts

Ayatellah Mohamed, Master candidate

CONTACT

01004600321ayatellah.ossman@dentistry.cu.edu.eg

Amir Hafez, Assistant professor

CONTACT

01100001278amir.hafez@dentistry.cu.edu.eg

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Ayatellah Mohamed

Study Record Dates

First Submitted

March 12, 2025

First Posted

March 18, 2025

Study Start

August 1, 2025

Primary Completion (Estimated)

September 1, 2026

Study Completion (Estimated)

October 1, 2027

Last Updated

March 18, 2025

Record last verified: 2025-03