Long-term Symptomatic Follow-up of Patients with Long COVID Syndrome

NCT06879535 | Active Not Recruiting

• 1 other identifier: 21-PI197
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to learn about the long-term evolution of long COVID. The main question it aims to answer is: Does the main symptoms of the patients diagnosed with long COVID aproximate to those of patients who have had COVID acute infection without devoloping long COVID? Participants will answer mailed survey questions about their main symptons.

Conditions

Long COVID

Keywords

Long COVID; Long-term follow-up; Symptoms; Scales

Outcome Measures

Primary Outcomes (8)

• Fatigue

  MFIS scale

  From enrollment to three years later

• Emotional disorders

  HADS scale

  From enrollment to three years later

• Sleep disorders

  PSQI

  From enrollment to three years later

• Cognitive impairments

  MFE-30

  From enrollment to three years later

• Dyspnea

  mMRC

  From enrollment to three years later

• Physical activity

  GPAQ

  From enrollment to three years later

• Quality of life (healthcare)

  SF-36

  From enrollment to three years later

• Pain (healthcare)

  EGDC

  From enrollment to three years later

Study Arms (2)

Cases

Patients diagnosed with long COVID

Controls

Patients who have had COVID acute infection without developing long COVID

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with long COVID who have been attended at the Internal Medicine Department at the Hospital Universitario Río Hortega from Valladolid

You may qualify if:

• patients older than 18 years old and younger than 75 years old
• patients who accepted to participate in the study
• patients who have had COVID acute infection
• patients who have long COVID (cases)

You may not qualify if:

• patients who refused to participate in the study at any time of the study
• patients whose diagnosis of long COVID was revoked during the study (cases)

Sponsors & Collaborators

• Hospital del Rio Hortega: lead

Study Sites (1)

Hospital Universitario Río Hortega

Valladolid, Valladolid, 47012, Spain

Location

MeSH Terms

Conditions

Post-Acute COVID-19 Syndrome

Condition Hierarchy (Ancestors)

COVID-19; Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Post-Infectious Disorders; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Médico Licenciado Especialista en Anestesiología y Reanimación

Study Record Dates

• First Submitted: March 12, 2025
• First Posted: March 17, 2025
• Study Start: March 28, 2022
• Primary Completion: March 28, 2025
• Study Completion: March 28, 2025
• Last Updated: March 17, 2025

Record last verified: 2025-03

Locations

ES (1)