NCT06878794

Brief Summary

To evaluate the safety and effectiveness of water triggered medical bioadhesive for meniscus tear repair

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
7mo left

Started Dec 2024

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress73%
Dec 2024Nov 2026

First Submitted

Initial submission to the registry

November 28, 2024

Completed
27 days until next milestone

Study Start

First participant enrolled

December 25, 2024

Completed
3 months until next milestone

First Posted

Study publicly available on registry

March 17, 2025

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2026

Last Updated

March 17, 2025

Status Verified

March 1, 2025

Enrollment Period

1.9 years

First QC Date

November 28, 2024

Last Update Submit

March 13, 2025

Conditions

Keywords

Meniscus tear

Outcome Measures

Primary Outcomes (3)

  • MOCART score

    Baseline (Before treatment), 6 and 12 months after treatment

  • Lysholm score

    Baseline (Before treatment), 3、 6 and 12 months after treatment

  • IKDC score

    Baseline (Before treatment), 3、 6 and 12 months after treatment

Secondary Outcomes (5)

  • T2 mapping

    Baseline (Before treatment),12 months after treatment

  • Equipment use and evaluation

    During operation

  • The occurrence of adverse events related to the test device

    12 months after treatment

  • The incidence of device related SAE requiring further surgical intervention within 12 months after surgical

    12 months after treatment

  • Equipment defect incidence rate

    During operation

Study Arms (2)

Control group

SHAM COMPARATOR

Using the meniscus suture system

Procedure: Using the meniscus suture system

Experimental group

ACTIVE COMPARATOR

Using medical biological glue for filling And Using the meniscus suture system

Combination Product: Using medical biological glue for filling And Using the meniscus suture system

Interventions

Using medical biological glue for filling And Using the meniscus suture system

Experimental group

Using the meniscus suture system

Control group

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • \. The patient is aged between 18 and 60 years old (including 18 and 60 years old), regardless of gender; 2. Unilateral meniscus tear of the knee joint; 3. Normal joint range of motion; 4. The subjects agree to participate in this trial and sign the "Subject Informed Consent Form".

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The First Affiliated Hospital of Ningbo University

Ningbo, Zhejiang, 315000, China

Location

Study Officials

  • Jiang Zhu

    First Affiliated Hospital of Ningbo University

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
NETWORK
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 28, 2024

First Posted

March 17, 2025

Study Start

December 25, 2024

Primary Completion (Estimated)

November 30, 2026

Study Completion (Estimated)

November 30, 2026

Last Updated

March 17, 2025

Record last verified: 2025-03

Data Sharing

IPD Sharing
Will not share

Locations