Translational Research GRICS-CineCardiac
Imagerie Cardiaque Ciné Par résonance magnétique en Respiration Libre
2 other identifiers
interventional
30
1 country
1
Brief Summary
This project is a pilot study which aims at showing the feasibility of free breathing cardiac MRI using GRICS (Generalized Reconstruction by Inversion of Coupled System)software in a clinical environment. The GRICS technique has been developed by the IADI (Diagnostic, Adaptive and Interventional Imaging)lab, Nancy, France. It enables free breathing MRI thanks to a reconstruction algorithm which provides artefact-free images based on raw MR data and physiological data from external sensors (respiratory belts, ECG. In this study, we want to acquire free breathing cardiac cine images during a standard cardiac MR exam and compare those data with the breath-hold ones.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Oct 2011
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2012
CompletedFirst Submitted
Initial submission to the registry
February 21, 2013
CompletedFirst Posted
Study publicly available on registry
March 17, 2025
CompletedApril 23, 2026
March 1, 2025
1 year
February 21, 2013
April 20, 2026
Conditions
Outcome Measures
Primary Outcomes (2)
Qualitative image reading by the radiologist
Feasibility of GRICS CardioCine : the radiologist responds to a questionnaire
1 Month
Quantitative image analysis by the radiologist
Feasibility of GRICS CardioCine : the radiologist responds to a questionnaire
1 Month
Secondary Outcomes (11)
Right ventricular end-diastolic volume
Day 1
Left ventricular end-diastolic volume
Day 1
Right ventricular end-systolic volume
Day 1
Left ventricular end-systolic volume
Day 1
Right ventricular systolic ejection volume
Day 1
- +6 more secondary outcomes
Study Arms (1)
Patients
EXPERIMENTALInterventions
Eligibility Criteria
You may qualify if:
- candidate to cardiac MR exam because of ischemic or dilated cardiopathy
- legally an adult
- having heath insurance
- having signed the consent form
You may not qualify if:
- dyspnea
- atrial fibrillation
- pain while lying on the back for a long time
- inability to follow a procedure
- contraindication to MRI
- contraindication to gadolinium chelate injection
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
CHU Brabois
Vandœuvre-lès-Nancy, 54511, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER GOV
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 21, 2013
First Posted
March 17, 2025
Study Start
October 1, 2011
Primary Completion
October 1, 2012
Study Completion
October 1, 2012
Last Updated
April 23, 2026
Record last verified: 2025-03