Management Strategy for Acute Cholecystitis in the Digestive Surgery Department and Geriatric Unit in Subjects Over and Under 75 Years

NCT06873295 | Completed

• 1 other identifier: Local /2023
• Study Type: observational
• Target: 424
• Locations: 1 country
• Sites: 1

Brief Summary

The management of these often frail elderly patients, with more comorbidities and declining functional capacities, is more complex and justifies a specific, tailored approach. Age is also associated with an increasing prevalence of gallstones. The disadvantages of "cold" surgery (longer hospital stay, higher cost, risk of disease recurrence in the interim, difficult surgery with more scar tissue due to repeated inflammation) have to be weighed against the high operative risk in the case of emergency surgery, leading to strict criteria for early cholecystectomy. These criteria are rarely met in geriatric patients, who thus enter a hospital cycle whose impact on morbidity and mortality, as well as on loss of autonomy, has been demonstrated in this population. What's more, the deteriorating general condition of frail elderly patients means that a number of them end up being definitively rejected for surgery, despite an initial strategy of cold cholecystectomy.

Conditions

Acute Cholecystitis

Outcome Measures

Primary Outcomes (1)

• Rate of patients with an initial cold cholecystectomy strategy who did not undergo surgery, died or underwent emergency surgery

  Percentage

  Up to 6 months, from date of first collection to date of end of collection

Eligibility Criteria

• Age: 19 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients hospitalized in the digestive surgery department and geriatric perioperative unit of the CHU de Nîmes with a diagnosis of acute cholecystitis.

You may qualify if:

• Patients over 18 years of age.
• Diagnosis of acute cholecystitis.
• Hospitalization in the digestive surgery department and geriatric perioperative unit of Nîmes University Hospital.

You may not qualify if:

• Patients under 18 years of age.

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Nīmes: lead

Study Sites (1)

Simonet Anne Clarisse

Nîmes, France

Location

MeSH Terms

Conditions

Cholecystitis, Acute

Condition Hierarchy (Ancestors)

Cholecystitis; Gallbladder Diseases; Biliary Tract Diseases; Digestive System Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 22, 2023
• First Posted: March 12, 2025
• Study Start: March 22, 2023
• Primary Completion: October 22, 2023
• Study Completion: October 22, 2024
• Last Updated: March 12, 2025

Record last verified: 2025-03

Locations

FR (1)