Neuropathic Pain and Traditional Medicine Syndromes in Herpes Zoster: a Cross-Sectional Study

NCT06870877 | Not Yet Recruiting DMC

• 1 other identifier: 78/HĐĐĐ-ĐHYD
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

This study investigates the relationship between neuropathic pain characteristics and Traditional Chinese Medicine (TCM) syndromes in patients with Herpes Zoster (HZ). The study aims to integrate objective pain assessment tools, such as the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) scale, with TCM diagnostic classifications to enhance individualized treatment strategies. Conducted at Le Van Thinh Hospital, Vietnam, this cross-sectional study includes 80 HZ patients, assessing their pain levels and corresponding TCM syndromes. The findings will contribute to a more comprehensive approach to pain management in Herpes Zoster.

Conditions

Herpes Zoster (HZ); Traditional Chinese Medicine (TCM)

Outcome Measures

Primary Outcomes (1)

• Neuropathic Pain Severity in Herpes Zoster Patients

  Measured using the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) pain scale. LANSS scores will be used to determine the severity of neuropathic pain in study participants.

  Baseline (Day 1)

Secondary Outcomes (1)

• Correlation Between Neuropathic Pain and Traditional Medicine Syndromes

  Baseline (Day 1).

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consists of 80 adult patients diagnosed with Herpes Zoster (shingles) who presented at Le Van Thinh Hospital, Ho Chi Minh City, Vietnam. These patients were experiencing neuropathic pain and were assessed using the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) scale. Participants were classified into Traditional Chinese Medicine (TCM) syndromes based on diagnostic criteria

You may qualify if:

• Adults aged ≥18 years
• Clinically diagnosed with Herpes Zoster (HZ) based on European Consensus Guidelines
• Experiencing neuropathic pain associated with HZ
• Willing to provide informed consent

You may not qualify if:

• History of chronic pain conditions unrelated to HZ
• Receiving immunosuppressive therapy or diagnosed with immunodeficiency disorders
• Patients who had already received antiviral or analgesic treatment before evaluation
• Patients unable or unwilling to provide informed consent

Sponsors & Collaborators

• Do Thanh Sang: lead

Study Sites (1)

Le Van Thinh Hospital

Ho Chi Minh City, Viet Nam, 700000, Vietnam

Location

MeSH Terms

Conditions

Herpes Zoster

Condition Hierarchy (Ancestors)

Varicella Zoster Virus Infection; Herpesviridae Infections; DNA Virus Infections; Virus Diseases; Infections

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: University of Medicine and Pharmacy at Ho Chi Minh City

Study Record Dates

• First Submitted: February 28, 2025
• First Posted: March 11, 2025
• Study Start: February 28, 2025
• Primary Completion: May 12, 2025
• Study Completion: May 12, 2025
• Last Updated: March 11, 2025

Record last verified: 2025-01

Locations

VN (1)