Energy CT in Imaging and Diagnosis of Gastric Cancer

NCT06869694 | Recruiting

• 1 other identifier: PC202409
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

Accurate preoperative prediction of risk stratification, treatment response, and survival prognosis in gastric cancer is important for improving clinical treatment decisions, prolonging patient survival, and improving patient quality of life. The purpose of this study is to investigate the performance of the multi-parametric magnetic resonance imaging (mpMRI) and Dual-/Muti-energy CT and photon-counting Detector CT(PCD-CT) in the diagnosis and management of gastric cancer.

Conditions

Gastric Cancer; CT

Keywords

CT; Gastric cancer

Outcome Measures

Primary Outcomes (1)

• Diagnostic and Predictive performance of Dual-/ Muti- energy CT and MRI in the treatment response and survival prognosis of gastric cancer

  Accuracy for both imaging techniques in the prediction of treatment response of gastric cancer.

  3years

Secondary Outcomes (1)

• The kappa value; One-way analysis of variance; ICC

  1year

Study Arms (1)

GC group

GC patients under ct and mri scan

Device: computerized tomography

Interventions

computerized tomography DEVICE

mpMRI and Photon-counting Detector CT scan

GC group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

For patients undergoing radical resection, abdominal exploration or palliative tumor resection, CT scanning and dynamic contrast-enhanced magnetic resonance DCE-MRI scanning shall be completed in GSI mode before operation; for patients undergoing neoadjuvant chemotherapy, CT scanning and dynamic contrast-enhanced magnetic resonance DCE-MRI scanning shall be completed in GSI mode before neoadjuvant chemotherapy at least, and if the above scanning mode can still be used during chemotherapy, it is the best choice. Signed informed consent form. Patients who were diagnosed with gastric cancer at various medical centers were included in this study

You may qualify if:

• Pathological biopsy confirmed gastric cancer;
• Surgery: patients undergoing radical gastrectomy. Patients undergoing exploratory abdominal surgery or palliative tumor resection were still included in the study when peritoneal metastasis or adjacent organ invasion was identified intraoperatively and radical surgical resection was not possible.

You may not qualify if:

• Refusal or inability to sign informed consent;
• CT or MRI images are poor or the focus is small and CT images are not clear;
• Patients with other tumors complicated with patients with important organ dysfunction.

Sponsors & Collaborators

• The First Affiliated Hospital of Zhengzhou University: lead

Study Sites (1)

The First Affiliated Hospital of Zhengzhou University

Zhengzhou, China, 450052, China

RECRUITING

MeSH Terms

Conditions

Stomach Neoplasms

Interventions

Tomography, X-Ray Computed

Condition Hierarchy (Ancestors)

Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Stomach Diseases

Intervention Hierarchy (Ancestors)

Image Interpretation, Computer-Assisted; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Radiographic Image Enhancement; Image Enhancement; Photography; Radiography; Tomography, X-Ray; Tomography

Central Study Contacts

Zihao Zhao, Dr

CONTACT

0371-66271387; zzh2020@163.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: The First Affiliated Hospital of Zhengzhou University

Study Record Dates

• First Submitted: March 6, 2025
• First Posted: March 11, 2025
• Study Start: September 1, 2024
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): September 1, 2028
• Last Updated: March 11, 2025

Record last verified: 2024-09

Locations

CN (1)