Role of CMR-FT in Assessment of HCM and Athlete's Heart.

NCT06859827 | Active Not Recruiting

• 1 other identifier: Soh-Med-25-2--MD
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Using cardiac MRI feature tracking to asses myocardial motion differences in athlete's heart and discovered hypertrophic cardiomyopathy patients to increase diagnostic accuracy of hypertrophic cardiomyopathy.

Conditions

Hypertrophic Cardiomyopathies; Athlete Heart

Keywords

Cardiac MRI feature tracking; Hypertrophic cardiomyopathy; Athlete's heart

Outcome Measures

Primary Outcomes (1)

• Use of cardiac MRI feature tracking in detection of myocardial deformation abnormalities and diagnostic confirmation and detection of hypertrophic cardiomyopathy.

  The main goal of the study is evaluating the role of Cardiac magnetic resonance feature tracking analysis in detection of myocardial deformation abnormalities in cases of hypertrophic cardio myopathy and compare it with physiological hypertrophy in athletes. Identification of strain patterns in hypertrophic cardiomyopathy.

  6months to 12 months

Study Arms (2)

hypertrophic cardiomyopathy patient

patient with hypertrophic cardiomyopathy

Athlete's

Athlete's with thick myocardium

Eligibility Criteria

• Age: 20 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Any age between 20 and 50 years either male or female with minor complains and suspected by Echo to be hypertrophic cardiomyopathy, athlete's exhibiting no symptoms.

You may qualify if:

• Patients suspected to be hypertrophic cardiomyopathy by echocardiography..
• Athletes and heavy workers,, healthy volunteers also included.

You may not qualify if:

• Patients with absolute or relative contraindications to magnetic resonance imaging (e.g intra-ocular metallic foreign body, claustrophobia, etc) or contra-indication to MRI contrast medium.
• Clinical morbidities with absolute contraindication to anesthesia during the examination in un-cooperative patients where sedation is required.

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag University hospital

Sohag, Sohag Governorate, 82511, Egypt

Location

MeSH Terms

Conditions

Cardiomyopathy, Hypertrophic

Condition Hierarchy (Ancestors)

Cardiomyopathies; Heart Diseases; Cardiovascular Diseases; Aortic Stenosis, Subvalvular; Aortic Valve Stenosis; Aortic Valve Disease; Heart Valve Diseases

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant lecturer diagnostic and interventional radiology

Study Record Dates

• First Submitted: February 28, 2025
• First Posted: March 5, 2025
• Study Start: December 15, 2024
• Primary Completion: November 15, 2025
• Study Completion: December 15, 2025
• Last Updated: March 5, 2025

Record last verified: 2025-02

Locations

EG (1)