NCT06858787

Brief Summary

This is a prospective pilot study to assess the validity of using a continuous glucose monitor (CGM) in diagnosing gestational diabetes mellitus (GDM). Pregnant individuals between the ages of 18-50 years old receiving prenatal care at Mount Sinai Hospital (e..g, E-Level clinic and Faculty Practice Associates) will be enrolled. Potential participants will be approached during their prenatal care appointments. Participants will complete an informed consent form for the study during their standard-of-care prenatal appointments at our institution.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
150

participants targeted

Target at P75+ for not_applicable

Timeline
23mo left

Started Oct 2025

Typical duration for not_applicable

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress24%
Oct 2025Apr 2028

First Submitted

Initial submission to the registry

February 27, 2025

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 5, 2025

Completed
7 months until next milestone

Study Start

First participant enrolled

October 2, 2025

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2028

Last Updated

January 15, 2026

Status Verified

January 1, 2026

Enrollment Period

2.5 years

First QC Date

February 27, 2025

Last Update Submit

January 13, 2026

Conditions

Outcome Measures

Primary Outcomes (3)

  • Blood glucose from CGM

    Blood glucose aggregate values from Dexcom G7 continuous glucose monitor (CGM)

    10 days from sensor application to completion of testing

  • Glucose Tolerance Test (GTT) values

    1-hour GTT values and 3-hour GTT values The glucose tolerance test is a lab test to check how the body moves sugar from the blood into tissues like muscle and fat. The test is used as standard of care to diagnose gestational diabetes.

    1 hour and 3 hours

  • Postpartum blood glucose

    A blood sugar test measures the amount of a sugar called glucose in a sample of blood.

    4 hours after childbirth

Study Arms (1)

Individuals receiving prenatal care at Mount Sinai Hospital

EXPERIMENTAL

Women receiving prenatal care at Mount Sinai Hospital to have 10-day application of continuous glucose monitor

Device: Continuous glucose monitor

Interventions

Device is a remote sensor applied to the upper extremity that continuously samples glucose of interstitial fluid and uploading results to a mobile application.

Individuals receiving prenatal care at Mount Sinai Hospital

Eligibility Criteria

Age18 Years - 50 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Ages 18-50
  • Singleton pregnancy between 24-32 weeks gestational age
  • Prenatal care and delivery at Mount Sinai Hospital

You may not qualify if:

  • Multiple fetal gestation
  • Preexisting diabetes
  • Concurrent use of steroids
  • Anomalous fetus
  • Insufficient prenatal care (identified as missing half the recommended visits or establishing care after 20 weeks gestation)
  • Unable to tolerate oral glucose test

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States

RECRUITING

Mount Sinai South Nassau

Oceanside, New York, 11572, United States

NOT YET RECRUITING

MeSH Terms

Conditions

Diabetes, Gestational

Condition Hierarchy (Ancestors)

Pregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesDiabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Officials

  • Angela Bianco, MD

    Icahn School of Medicine at Mount Sinai

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Nicola F Tavella, MPH

CONTACT

Victoria Ly, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

February 27, 2025

First Posted

March 5, 2025

Study Start

October 2, 2025

Primary Completion (Estimated)

April 1, 2028

Study Completion (Estimated)

April 1, 2028

Last Updated

January 15, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations