NCT06848543

Brief Summary

The investigators will follow probability-based cohorts of adult non-medical marijuana users (N=1,500; ages 21+) and susceptible adolescents and young adults (AYA) users (N=1,000; ages 15-20) over four years. The investigators will use a prospective survey to collect marijuana use information and will conduct volumetric choice experiments (VCEs) where participants choose quantities to purchase among three legal product prototypes: flower, edible, and concentrate; and one illegal flower product, under simulated retail marijuana tax structures. The presentation of edibles and concentrates will change over time to capture the range of product varieties in the market and to accommodate new products and characteristics as they evolve. Choice experiments including VCEs use a series of manipulations as a measurement device to elicit preferences for products and consumption. Therefore, the experimental design is within-subjects with repeated measures, which allow for causal identifications of the impact of design attributes (e.g., tax bases and rates) on preference and consumption outcomes. The attributes and levels are selected to reflect THC levels in the market, existing (weight, price, tiered price by forms) and novel (potency) tax bases, existing (10%-40% of retail price or equivalent in other bases) and potential (high 60% and 80% of retail prices or equivalent) tax rates, and price distribution for each product. Price distribution levels (5 to 95 percentiles) will come from our price data collection and will be updated over time and vary by participants' state and locality of residence. Before the experiment, study personnel will instruct participants 1) how to answer the choice experiment question, including considering their weekly expenditures when answering VCE questions; 2) that there is no access to other products, no stockpiling, no selling or giving away products to others, etc., to ensure that participants choose products that reflect their usual purchase patterns for self-use; 3) that there are no right or wrong responses. Study personnel will instruct participants to answer all questions honestly, thoughtfully, and to the best of their understanding as if they were actually in this situation, to reduce hypothetical bias; 4) that there may be potential costs or issues associated with purchasing illegal products, including risks of penalties, undefined potency, possible contamination, and inconsistent product quality; and 5) that participants should keep their weekly budget in mind when making purchase choices of the products. In VCEs, the investigators will manipulate THC levels, tax rates and bases, and price levels. Participants will be asked to answer the following: "Imagine these are the marijuana products that you (participants) can purchase for non-medical use, how many of each product would you (participants) most likely buy next time?" Participants can choose more than one product, and as they choose quantities, the total balance will be displayed. To make the tasks easier, study personnel will 1) set a warning to inform participants if their reported budget exceeds their weekly budget for spending; 2) provide a dropdown list for quantities or, if they would like more units than the listed, they can fill in a number; and 3) all products are described as high-quality to allow for a comparison of prices. Half of the participants will be randomized to see itemized pre-tax tag price, excise taxes, and sales taxes, as requested in some states (e.g., Illinois); the other half will be randomized to see only prices that are inclusive of excise taxes. This will allow us to whether excise taxes are more effective when applied at checkout compared to hidden in the tag prices.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,696

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jun 2024

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 17, 2024

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

February 14, 2025

Completed
13 days until next milestone

First Posted

Study publicly available on registry

February 27, 2025

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 10, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 10, 2026

Completed
Last Updated

May 11, 2026

Status Verified

April 1, 2026

Enrollment Period

1.8 years

First QC Date

February 14, 2025

Last Update Submit

May 7, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Hypothetical purchase decisions (Unit purchased)

    Number of units that participants intend to purchase, if taxes and prices are set at a certain level.

    Measures will be collected at baseline, 6 month follow up, 12 month follow up, and the 18 month follow up.

Secondary Outcomes (1)

  • Whether to make a hypothetical purchase

    Measures will be collected at baseline, 6 month follow up, 12 month follow up, and the 18 month follow up.

Study Arms (3)

Tax structure arm 1

OTHER

Participants are randomized into seeing WEIGHT based taxes for recreational cannabis, then they make hypothetical purchases in responses to products with different THC levels, prices, and taxes.

Behavioral: Arm 1 Intervention

Tax structure arm 2

OTHER

Participants are randomized into seeing PRICE based taxes for recreational cannabis, then they make hypothetical purchases in responses to products with different THC levels, prices, and taxes.

Behavioral: Arm 2 Intervention

Tax structure arm 3

OTHER

Participants are randomized into seeing potency based taxes for recreational cannabis, then they make hypothetical purchases in responses to products with different THC levels, prices, and taxes.

Behavioral: Arm 3 intervention

Interventions

Arm 1 intervention is weight based taxes on cannabis, where participants make hypothetical purchases under weight based taxes.

Tax structure arm 1

Arm 2 intervention is price based taxes on cannabis, where participants make hypothetical purchases under price based taxes.

Tax structure arm 2

Arm 3 intervention is potency based taxes on cannabis, where participants make hypothetical purchases under potency based taxes.

Tax structure arm 3

Eligibility Criteria

Age15 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Adults:
  • aged 21 years and older
  • must be past-30-day dual users of recreational marijuana Adolescents and young adults
  • ages 15-20
  • susceptible to marijuana use

You may not qualify if:

  • adults older than 21 years who are not using marijuana for recreational purposes
  • youth under age 15
  • teens and young adults who are not susceptible to marijuana use

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Center for Tobacco Research OSU

Columbus, Ohio, 43214, United States

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Masking Details
No masking. Participants are assigned to different tax structures and answer choice experiment questions when prices, taxes, and THC levels of cannabis products change
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: Design method: An orthogonal experimental design that identifies the effects of main attributes (4 THC levels, 3 excise tax bases, 5 tax rate levels, 5 pre-tax tag price levels) will result in 300 (3×4×52) choice scenarios. The investigators will use the Ngene software and a D-optimal design to select a subset of all choice scenarios that significantly reduce the total number of choice sets while remaining efficient for model identification. To reduce fatigue, the investigators will develop 2 blocks each containing 12 choice sets, and participants will be randomly assigned to one of these blocks. The order of the 12 choice sets will also be randomized. Before the experiment, participants will be instructed that their answers will be used for research to advance public health and that they should answer truthfully.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

February 14, 2025

First Posted

February 27, 2025

Study Start

June 17, 2024

Primary Completion

April 10, 2026

Study Completion

April 10, 2026

Last Updated

May 11, 2026

Record last verified: 2026-04

Locations