Graded Activity Training and Task- Oriented Training on Post-Stroke Fatigue

NCT06846177 | Recruiting DMC

• 1 other identifier: Sahar Khalid
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this randomized controlled trial is to determine the effects of Graded Activity Training and Task Oriented Training on Fatigue in Post-Stroke Patients. Until now there is very limited work found on fatigue so this will increase quality of life in stroke patients and potentially reduce burden on healthcare system.

Conditions

Post-Stroke Fatigue

Keywords

Task oriented training; Graded activity training; Post stroke; Fatigue

Outcome Measures

Primary Outcomes (1)

• Fatigue Assessment scale (FAS)

  The FAS is a 10-item scale is used to evaluate symptoms of chronic fatigue. In contrast to other similar measures description of the fatigue experienced is presented for the total score of l\<22 indicates normal, levels of fatigue between 22 to 34 indicates mild to moderate fatigue and score 35 or more indicates severe fatigue

  6 weeks

Secondary Outcomes (2)

• Timed Up and go test(Mobility)

  6 weeks

• Dynamic gait index (Gait)

  6 weeks

Other Outcomes (2)

• Checklist individual strength-Fatigue (CIS-F) (Screening tool)

  1st week

• Borg's Rating of Perceived Exertion (Monitoring Tool

  6 weeks

Study Arms (2)

Graded Activity Training

EXPERIMENTAL

Graded Activity Training

Other: Graded Activity Training

Task Oriented Training

ACTIVE COMPARATOR

Task Oriented Training

Other: Task-Oriented Training

Interventions

Graded Activity Training OTHER

4 types of progressive activities of 2 hour session two times/week with resting periods of 30 mins. Activities consist of treadmill walk ,walk on floor, core muscles exercises ,home tasks . To ensure the proper heart rate and loads during the exercises, measurements of individual heart rate and muscle strength are taken during the first session (baseline) with HR Tracking portable device and also during the session to continuously monitor HR of the Patient. To withdraw or adjust the training intensity for each patient Borg's Scale of Perceived Exertion is used throughout the session for monitoring Training intensity of endurance, muscle training, individual's effort and exertion level.

Graded Activity Training

Task-Oriented Training OTHER

4 task oriented physical fitness activities which include walk on floor, walk on inclined surface using treadmill ,sit to stand , stair climbing and descending for duration of 2 hour session with frequent breaks. Each treatment session began with 10 minutes of warm-up exercise, which consisted of passive stretching of the calf muscles, hamstring, and hip adductors. The level of difficulty and frequency for each task were gradually increased during the 6 weeks with the patients consent.10 minutes of cool down at the end of each treatment session.

Task Oriented Training

Eligibility Criteria

• Age: 40 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Both male and female of age 40 to 60 years.
• Patient with both ischemic or hemorrhagic stroke.
• Patient with both right and left hemiplegia.
• Checklist Individual (CIS-F) fatigue score of 40 or more.
• Patients who had sustained a stroke more than 4 months before recruitment.
• Patients who can independently walk for 10 meters (about 33 feets)

You may not qualify if:

• Patients with severe comorbid health conditions (such as cardiac diseases, pulmonary diseases like COPD, Orthopedic Conditions Arthritis, joint replacements).
• Patients with uncontrolled diabetes, hypertension, Depression and Anxiety.
• Patients who are not willing to participate.
• Patient with any medications that can affect their ability to engage in physical training program like Antidepressants, Beta-Blockers, corticosteroids etc.
• Pregnant women.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Helping Hand Institute of Rehabilitation Sciences

Mansehra, KPK, Pakistan

RECRUITING

MeSH Terms

Conditions

Fatigue

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Dr.Aroosa Tariq, MS-NMPT

  Riphah International University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Dr.Aroosa Tariq, MS-NMPT

CONTACT

03161578156; aroosa.tariq@riphah.edu.pk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 20, 2025
• First Posted: February 25, 2025
• Study Start: March 1, 2025
• Primary Completion: March 20, 2026
• Study Completion: April 25, 2026
• Last Updated: March 11, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)