Effects of Dual-Task and Progressive Wall Squat Training in Stroke Survivors

NCT06845683 | Completed DMC

• 1 other identifier: REC/24/0211 Barira Shahid
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

To determine the Effects of Dual-Task and Progressive Wall Squat Training on Cognition, Balance and Functional mobility in Stroke Survivors.

Conditions

Stroke Ischemic

Keywords

Balance; cognition; dual-task; functional mobility; stroke survivors; wall squat

Outcome Measures

Primary Outcomes (3)

• MOCA (Montreal Cognitive Assessment)

  A well-liked screening method for identifying the presence of cognitive impairment is the MoCA. It takes about ten minutes to finish. It assesses language, abstract reasoning, executive function, orientation, delayed recall, attention, and visuospatial skills. The MoCA is more sensitive and specific than the MMSE because it covers a wider range of domains.

  8 weeks

• Tinneti POMA (Balance, gait)

  The Tinetti Scale is a tool for assessing gait and balance. The test is used clinically to evaluate changes in gait time and balance, as well as to ascertain a subject's current level of mobility. The two sub-scales that make up the total POMA (POMA-T) are the gait evaluation scale (also known as the POMA-G) and the balance evaluation scale (also known as the POMA-B). The maximum score is 28 points; specifically, the POMA-B has a maximum score of 16 and the POMA-G has a maximum score of 12.

  8 weeks

• Rivermead mobility index

  RMI is a measure that evaluates a patient's degree of mobility .There are 14 questions on it, along with a section on observations. This index evaluates an individual's ability to do tasks like getting out of bed, sitting, maintaining balance, standing up, standing unassisted, moving around, walking indoors and outside, climbing and descending stairs, picking up objects off the floor, taking a shower, and running. Every activity receives one point, if at all possible. If the score is less than 14, it suggests that the person has mobility problems; if the score is 15, it means they don't have any problems at all

  8 weeks

Study Arms (2)

combining progressive wall squats with cognitive training

EXPERIMENTAL

Group A will receive dual-task intervention (combining progressive wall squats with cognitive training) along with routine rehabilitation. The group will undergo 45 minute treatment session three times per week over an eight weeks period, focusing on gradually intensifying the progressive wall squat exercises with careful supervision to ensure safety and proper form along with cognitive tasks.

Other: Group A

progressive wall squats

ACTIVE COMPARATOR

Group B will receive single-task intervention (involving progressive wall squats) along with routine rehabilitation. A routine rehabilitation comprising slow sustained stretching (with a hold time of 10 seconds per stretch, totaling 10 repetitions per session) and active range of motion exercises (10 repetitions per session) targeting both the upper and lower extremities. The group will undergo 45 minute treatment session three times per week over an eight weeks period.

Other: Group B

Interventions

Group A OTHER

Progressive wall squat exercises will commence with a knee flexion angle of 135°, instructed to hold this position for 20 seconds, exercise progresses, the knee joint angle will be decreased by 10° until reaching the 95° stage or until participants can no longer maintain the knee joint angle within 5° of the target value due to volitional fatigue. Cognitive tasks during the intervention, including the recall of words and counting forward (1, 4, 7, 10...) and backward (...10, 7, 4, 1) by adding 3 to the digits. Sustained stretching (with a hold time of 10 seconds per stretch, totaling 10 repetitions per session) and active range of motion exercises (10 repetitions per session) targeting both the upper and lower extremities in routine rehabilitation.

Also known as: Dual task training (Wall squats + cognitive training along with routine rehabilitation

combining progressive wall squats with cognitive training

Group B OTHER

Progressive wall squat exercises will commence with a knee flexion angle of 135°, instructed to hold this position for 20 seconds, exercise progresses, the knee joint angle will be decreased by 10° until reaching the 95° stage or until participants can no longer maintain the knee joint angle within 5° of the target value due to volitional fatigue. Sustained stretching (with a hold time of 10 seconds per stretch, totaling 10 repetitions per session) and active range of motion exercises (10 repetitions per session) targeting both the upper and lower extremities in routine rehabilitation.

Also known as: single-task intervention (Wall squats) along with routine rehabilitation

progressive wall squats

Eligibility Criteria

• Age: 45 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age: Stroke patients aged 45 to 65 years.
• Individuals with a single ischemic stroke.
• Within the first 2 months post-stroke. (Subacute stage)
• Medically stable without acute conditions interfering with exercise.
• Mini-Mental State Examination (MMSE) score≥24
• Ability to walk 10m without assistance

You may not qualify if:

• Unstable Medical Conditions (cardiovascular, respiratory, or other medical conditions)
• Recent Stroke or Medical Event
• Other Neurological Conditions such as Presence of other neurological conditions (e.g., Parkinson's disease).
• Uncontrolled Hypertension: Systolic BP \>160 mm Hg or diastolic BP \>100 mm Hg

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Society Hospital

Lahore, Punjab Province, 54840, Pakistan

Location

Related Publications (6)

• Morice E, Moncharmont J, Jenny C, Bruyneel AV. Dancing to improve balance control, cognitive-motor functions and quality of life after stroke: a study protocol for a randomised controlled trial. BMJ Open. 2020 Sep 30;10(9):e037039. doi: 10.1136/bmjopen-2020-037039.

  PMID: 32998921 BACKGROUND

• Buvarp D, Rafsten L, Sunnerhagen KS. Predicting Longitudinal Progression in Functional Mobility After Stroke: A Prospective Cohort Study. Stroke. 2020 Jul;51(7):2179-2187. doi: 10.1161/STROKEAHA.120.029913. Epub 2020 Jun 17.

  PMID: 32568652 BACKGROUND

• Lee Y, Kim K. The influence of Gait Training Combined with Portable Functional Electrical Stimulation on motor function, balance and gait ability in stroke patients. J Back Musculoskelet Rehabil. 2022;35(6):1171-1178. doi: 10.3233/BMR-210154.

  PMID: 35754258 BACKGROUND

• Hurd MD, Goel I, Sakai Y, Teramura Y. Current status of ischemic stroke treatment: From thrombolysis to potential regenerative medicine. Regen Ther. 2021 Oct 12;18:408-417. doi: 10.1016/j.reth.2021.09.009. eCollection 2021 Dec.

  PMID: 34722837 BACKGROUND

• Spano B, Lombardi MG, De Tollis M, Szczepanska MA, Ricci C, Manzo A, Giuli S, Polidori L, Griffini IA, Adriano F, Caltagirone C, Annicchiarico R. Correction: Spano et al. Effect of Dual-Task Motor-Cognitive Training in Preventing Falls in Vulnerable Elderly Cerebrovascular Patients: A Pilot Study. Brain Sci. 2022, 12, 168. Brain Sci. 2024 Apr 11;14(4):370. doi: 10.3390/brainsci14040370.

  PMID: 38672060 BACKGROUND

• Kuriakose D, Xiao Z. Pathophysiology and Treatment of Stroke: Present Status and Future Perspectives. Int J Mol Sci. 2020 Oct 15;21(20):7609. doi: 10.3390/ijms21207609.

  PMID: 33076218 BACKGROUND

MeSH Terms

Conditions

Ischemic Stroke

Condition Hierarchy (Ancestors)

Stroke; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Aruba Saeed, PhD

  Riphah International University Pakistan

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Masking Details: participants and outcome assesssors wtll be kept blinded about the intervention which the patients will be going to receive.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Assignment

Study Record Dates

• First Submitted: February 20, 2025
• First Posted: February 25, 2025
• Study Start: October 30, 2024
• Primary Completion: March 15, 2025
• Study Completion: March 15, 2025
• Last Updated: April 9, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)