Treatment of Deficient Interdental Papilla Using Albumin-platelets Rich Fibrin

NCT06842277 | Active Not Recruiting Phase 2

• 1 other identifier: 20124
• Study Type: interventional
• Target: 10
• Locations: 1 country
• Sites: 2

Brief Summary

The goal of this ( A case series, clinical trial ) is treatment of deficient interdental papilla in patients who have interdental papillary loss class 1 or 2 in maxillary or mandibular anterior region with plaque index and gingival index less than 1 and the selected sites had distance between contact point and inter proximal bone crest less than 7mm and probing depth less than 4mm. Hypothesis: Albumin-PRF is an efficient treatment of deficient interdental papilla. The primary outcome ( distance between the contact point and papillary tip will be measured by periodontal probe) The participants will practice good oral hygiene measures

Conditions

Interdental Papilla Reconstruction; Deficient Interdental Papilla

Keywords

Reconstruction of deficient interdental papilla using injectable albumin platelets rich fibrin

Outcome Measures

Primary Outcomes (1)

• Distance between contact point and papilla tip (Height of black triangle)

  The distances between the contact point and papilla tip will be measured clinically by a periodontal probe

  6 months

Study Arms (1)

patients whose had deficient interdental papilla

OTHER

treatment of patients whose had deficient interdental papilla using injectable Albumin -platelets rich fibrin

Biological: Injectable albumin platelets rich fibrin

Interventions

Injectable albumin platelets rich fibrin BIOLOGICAL

Using injectable albumin platelets rich fibrin which is minimally invasive non surgical technique with autogenous , slow degradable and rich in leukocytes and growth factors material .

patients whose had deficient interdental papilla

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients' complaint from poor esthetics and unappealing black triangles in anterior sextant.
• Patients had well -aligned maxillary teeth, no caries, no proximal restoration, fixed prosthesis, or any orthodontic appliance.
• Patients had at least one class 1or 2 interdental papilla loss in maxillary or mandibular anterior regions.
• Patients had at selected sites, distance between contact point and inter proximal bone crest less than 7mm and probing depth less than 4mm.
• Patients had plaque index and gingival index less than 1.

You may not qualify if:

• Patient had advanced periodontal problems (advanced bone and soft tissue loss).
• Patients had a systemic condition affect blood components and healing.
• Smoker patients.
• Patients who are pregnant.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (2)

Faculty of Dentistry , Cairo University

Giza, Giza Governorate, 12613, Egypt

Location

Faculty of Dentistry Cairo University

Giza, Giza Governorate, 12613, Egypt

Location

Study Design

• Study Type: interventional
• Phase: phase 2
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Master Student

Model Details: A case series

Study Record Dates

• First Submitted: February 19, 2025
• First Posted: February 24, 2025
• Study Start: February 18, 2025
• Primary Completion: December 30, 2025
• Study Completion: April 1, 2026
• Last Updated: February 25, 2025

Record last verified: 2025-02

Locations

EG (2)