Analysis of Radiographic Indices in Carpal Tunnel Syndrome

NCT06841809 | Completed

• 1 other identifier: AnkaraTRH-FTR-NK-03
• Study Type: observational
• Target: 275
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to compare wrist radiographic indices in patients with idiopathic carpal tunnel syndrome (CTS) with normal cases. The investigators believe that the investigators can contribute to the development of new treatment strategies by determining the radiographic features that contribute to the development of CTS.

Conditions

Carpal Tunnel Syndrome (CTS); Wrist; X-Ray; Radiography

Keywords

Carpal Tunnel Syndrome (CTS); wrist; X-Ray

Outcome Measures

Primary Outcomes (1)

• Measurement of Radiographic Indices

  Radio-lunate Angle (RLA): The distance between the tangential line connecting the two distal poles of the lunate root and the line drawn perpendicular to the central medullary canal of the distal radius.

  up to 12 weeks

Secondary Outcomes (10)

• Boston Carpal Tunnel Syndrome Questionnaire

  up to 12 weeks

• Electromyography Examination

  up to 12 weeks

• Measurement of Radiographic Indices

  up to 12 weeks

• Measurement of Radiographic Indices

  up to 12 weeks

• Measurement of Radiographic Indices

  up to 12 weeks

Study Arms (2)

Case

Patients referred to the EMG clinic and diagnosed with carpal tunnel syndrome were selected. All of these patients underwent bilateral EMG.

Control

The control group was randomly selected from patients who applied with other hand and wrist complaints during the same period and who had wrist radiographs, and who were matched with the study group in terms of age and gender.

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The case group will consist of patients referred to the EMG clinic and diagnosed with carpal tunnel syndrome (CTS). All of these patients will undergo bilateral EMG. The control group was randomly selected from patients with hand and wrist complaints, who were matched with the study group in terms of age and gender, and who had hand complaints other than CTS.

You may qualify if:

• Not having had any previous surgical procedures on the hand or wrist
• Not having had a major hand or wrist trauma
• No structural disorders in the bone structure

You may not qualify if:

• Being under 18 years of age
• History of major hand-wrist trauma or surgery
• Acromegaly
• Rheumatoid arthritis
• Systemic lupus erythematosus
• GUT arthritis
• Psoriatic arthritis

Sponsors & Collaborators

• Ankara Training and Research Hospital: lead

Study Sites (1)

Ankara Training and Research Hospital, University of Health Sciences, Department of Physical Therapy and Rehabilitation

Ankara, Altindag, 06230, Turkey (Türkiye)

Location

Related Publications (10)

• Uysal T, Ramoglu SI, Basciftci FA, Sari Z. Chronologic age and skeletal maturation of the cervical vertebrae and hand-wrist: is there a relationship? Am J Orthod Dentofacial Orthop. 2006 Nov;130(5):622-8. doi: 10.1016/j.ajodo.2005.01.031.

  PMID: 17110259 BACKGROUND

• Ferreira Branco D, Bouvet C, Hamard M, Beaulieu JY, Poletti PA, Boudabbous S. Reliability of radio-ulnar and carpal alignment measurements in the wrist between radiographs and 3D imaging. Eur J Radiol. 2022 Sep;154:110417. doi: 10.1016/j.ejrad.2022.110417. Epub 2022 Jun 22.

  PMID: 35772337 BACKGROUND

• Garcia-Elias M, An KN, Amadio PC, Cooney WP, Linscheid RL. Reliability of carpal angle determinations. J Hand Surg Am. 1989 Nov;14(6):1017-21. doi: 10.1016/s0363-5023(89)80053-x.

  PMID: 2584642 BACKGROUND

• Okan N, Caboglu F, Mertoglu T, Durakbasa O, Gorgec M. [The measurement of wrist kinematics in children 4 to 16 years old and the comparison of the scapholunate distance with adult values]. Acta Orthop Traumatol Turc. 2004;38(1):30-3. Turkish.

  PMID: 15054295 BACKGROUND

• Wang YC, Tseng YC, Chang HY, Wang YJ, Chen CJ, Wu DY. Gender differences in carpal height ratio in a taiwanese population. J Hand Surg Am. 2010 Feb;35(2):252-5. doi: 10.1016/j.jhsa.2009.11.010.

  PMID: 20141895 BACKGROUND

• Vaezi T, Hassankhani GG, Ebrahimzadeh MH, Moradi A. Evaluation of Normal Ranges of Wrist Radiologic Indexes in Mashhad Population. Arch Bone Jt Surg. 2017 Nov;5(6):451-458.

  PMID: 29299502 BACKGROUND

• Ar Altamimi A, Gharaibeh MA, Shokor MA, Dawod MS, Alswerki MN, Al-Odat OM, Elkhaldi RH. Association between carpal height ratio and ulnar variance in normal wrist radiography. BMC Musculoskelet Disord. 2024 Jul 9;25(1):524. doi: 10.1186/s12891-024-07647-z.

  PMID: 38982384 BACKGROUND

• Taillac H, Holzgrefe R, Hao KA, Hones KM, Wright TW, King JJ, Satteson E, Matthias RC. Intercarpal Angles on Hand Versus Wrist Films: Are Hand Radiographs Sufficient for Assessing Intercarpal Angles? J Hand Surg Am. 2024 Dec;49(12):1273.e1-1273.e6. doi: 10.1016/j.jhsa.2023.04.012. Epub 2023 May 27.

  PMID: 37245153 BACKGROUND

• Sarhan MY, Altamimi AA, Gharaibeh MA, Akel A, Abu Shokor M, Salem OA, Balbisi B, Abu-Jeyyab M. Evaluation of Normal Ranges of Wrist Radiologic Indexes in Jordanian Population. Orthop Rev (Pavia). 2024 Aug 3;16:120049. doi: 10.52965/001c.120049. eCollection 2024.

  PMID: 39105053 BACKGROUND

• Koca N, Nazligul NK. Evaluation of wrist radiographic indices in people with idiopathic carpal tunnel syndrome: a prospective cross-sectional study. Ann Phys Rehabil Med. 2026 Jan 8;69(2):102068. doi: 10.1016/j.rehab.2025.102068. Online ahead of print.

  PMID: 41512671 DERIVED

MeSH Terms

Conditions

Carpal Tunnel Syndrome

Condition Hierarchy (Ancestors)

Median Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: February 16, 2025
• First Posted: February 24, 2025
• Study Start: February 16, 2025
• Primary Completion: May 1, 2025
• Study Completion: July 1, 2025
• Last Updated: July 31, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)