Effect of Motor Cognitive Interference on Cognition and Quality of Life on Patients with Multiple Sclerosis

NCT06839924 | Active Not Recruiting DMC

• 1 other identifier: P.T>REC/012/005458
• Study Type: interventional
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

Is there an effect of Cognitive Motor Interference on Cognition and quality of life on Multiple Sclerosis patients.

Conditions

Multiple Sclerosis, MS

Keywords

Multiple Sclerosis; MS; Cognition; Cognitive Motor Interference; quality of life; Qol

Outcome Measures

Primary Outcomes (1)

• Cognition (working memory and divided attention)

  cognition domains including working memory and divided attention will be assessed by rehacom V 6.10.2.0 software

  baseline assessment and after 12 sessions of Cognitive motor interference 3 sessions per weak for 4 weaks

Secondary Outcomes (1)

• A health-related quality of life

  Baseline assessment and after 12 sessions of Cognitive motor interference 3 sessions per weak for 4 weaks

Study Arms (2)

Study group

EXPERIMENTAL

Study group will uses Cognitive Motor Interference

Behavioral: Cognitive Motor Interference

Control group will uses traditional physical therapy

ACTIVE COMPARATOR

control group will use traditional physiotherapy

Behavioral: traditional physical therapy

Interventions

Cognitive Motor Interference BEHAVIORAL

Dual task that uses cognitive in addition to Motor training

Study group

traditional physical therapy BEHAVIORAL

physiotherapy program including exercises in addition to physical modalities

Control group will uses traditional physical therapy

Eligibility Criteria

• Age: 25 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• M S patients complain of Mild Cognitive impairment according to Modified Mini Mental State (MMSE).
• Patients with remission and relapse, primary and secondary progression types of MS.
• Age between 25 and 45 years.
• Patients from both gender.

You may not qualify if:

• patients have visual disorders
• patients have auditory disturbance
• Non educational patients.
• Patients with psychiatric disorders.
• Patients with mod to severe cognitive impairment according to MMSE

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Physical Therapy Cairo University

Giza, Dokki, 11732, Egypt

Location

MeSH Terms

Conditions

Multiple Sclerosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: external investigator and assessor will be enrolled
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer Assisstant

Study Record Dates

• First Submitted: December 16, 2024
• First Posted: February 21, 2025
• Study Start: December 10, 2024
• Primary Completion: June 12, 2025
• Study Completion: August 1, 2025
• Last Updated: February 21, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)