Assessing the Impact of Additional Serratus Anterior Block Within 24-Hour on Postoperative Pain After Rhomboid Intercostal Block in VATS Patients

NCT06838039 | Recruiting

• 1 other identifier: Re27-06-024
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Title: Assessing the Impact of Additional Serratus Anterior Block on Postoperative Pain After Rhomboid Intercostal Block in VATS Patients Purpose: This randomized controlled trial aims to evaluate whether the addition of a Serratus Anterior Plane Block (SAPB) to the standard Rhomboid Intercostal Block (RIB) improves postoperative pain management in patients undergoing Video-Assisted Thoracoscopic Surgery (VATS). Study Design:

• Type: Randomized Controlled Trial (RCT)
• Participants: 50 patients aged 18 -70 requiring VATS, randomized into two groups: one receiving RIB alone, and the other receiving RIB + SAPB.
• Duration: Pain and opioid consumption will be measured within 48 hours post-surgery.
• Outcome Measures: Pain levels using the Visual Analog Scale (VAS), opioid usage, and patient satisfaction. Significance: The study addresses the gap in research regarding the combined use of SAPB and RIB in pain control for VATS. It hypothesizes that the combination will lead to better pain relief and reduced opioid dependence compared to RIB alone.

Conditions

Post Operative Pain; VATS

Keywords

Postoperative Pain Management; Video-Assisted Thoracoscopic Surgery

Outcome Measures

Primary Outcomes (1)

• Pain Severity

  Postoperative pain will be assessed using the Visual Analog Scale for pain which higher score mean more pain at various time intervals (e.g., 1,12, 24, 36 and 48 hours post-surgery).

  48 hours post-surgery.

Secondary Outcomes (1)

• Opioid Consumption

  48 hours post-surgery.

Study Arms (2)

Arm 1 (RIB Only)

EXPERIMENTAL

Participants receive a Rhomboid Intercostal Block (RIB) as the sole regional anesthesia technique for postoperative pain management after VATS

Procedure: Rhomboid Intercostal Block (RIB)

Arm 2 (RIB + SAPB)

EXPERIMENTAL

Participants receive both RIB and SAPB within 24 hours postoperatively

Procedure: Rhomboid Intercostal Block (RIB) + Serratus Anterior Plane Block (SAPB)

Interventions

Rhomboid Intercostal Block (RIB) + Serratus Anterior Plane Block (SAPB) PROCEDURE

A combination of two regional anesthesia techniques, Rhomboid Intercostal Block (RIB) and Serratus Anterior Plane Block (SAPB),(THE SAPB will received within 24 hours after RIB) administered under ultrasound guidance. SAPB targets the lateral cutaneous branches of the thoracic nerves, complementing the pain relief provided by RIB. This combination is used in Arm 2 to enhance postoperative analgesia.

Arm 2 (RIB + SAPB)

Rhomboid Intercostal Block (RIB) PROCEDURE

Rhomboid Intercostal Block (RIB) A regional anesthesia technique administered under ultrasound guidance for postoperative pain relief. This will be used as the sole intervention in Arm 1.

Arm 1 (RIB Only)

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged 18-70 years.
• Patients undergoing Video-Assisted Thoracoscopic Surgery (VATS).
• Classified as ASA physical status I-III (low to moderate surgical risk).
• Ability to provide informed consent and follow study protocols.

You may not qualify if:

• Known allergy or hypersensitivity to local anesthetics.
• Presence of bleeding disorders or anticoagulant use.
• History of chronic opioid use or opioid dependence.
• Anatomical abnormalities or conditions preventing the application of regional anesthesia (e.g., chest wall deformities).
• Presence of neurological disorders affecting pain perception.
• Cognitive impairments, language barriers, or inability to communicate effectively.
• Pregnancy or breastfeeding.
• Refusal or inability to provide informed consent.

Sponsors & Collaborators

• Al-Quds University: lead

Study Sites (1)

Al Ahli hospital

Hebron, Palestinian Territories

RECRUITING

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Central Study Contacts

Mohammed Adel Adwan, MD

CONTACT

00970594393480; maadwan123m@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 20, 2025
• First Posted: February 20, 2025
• Study Start: April 1, 2025
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: August 28, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)