Evaluation of Voice in Behcet's

NCT06836817 | Not Yet Recruiting

• 1 other identifier: voice in Behcet's Disease
• Study Type: observational
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

Behçet's disease (BD) is a systemic inflammatory condition of unknown origin with no definite aetiopathogenetic pathways accepted worldwide. To date, only a few studies have investigated laryngeal involvement in BD and data about this are scarce. For these reasons, the present study focuses on verifying the occurrence of vocal cord involvement in patients with BD, identifying potential correlations with specific demographic, clinical, and therapeutic characteristics.

Conditions

Behcet Disease

Outcome Measures

Primary Outcomes (5)

• laryngoscopic pictures

  abnormal anatomical laryngeal findings like laryngeal congestion, bleeding, vocal fold polyps, cysts, nodules

  baseline

• frequency

  frequency in hertz

  baseline

• jitter

  jitter in percentage %

  baseline

• shimmer

  shimmer in decibl

  baseline

• harmonic to noise ratio

  harmonic to noise ratio in decibl

  baseline

Study Arms (2)

Group I

Group I will comprise of the 30 patients with Behçet's disease (BD).

Other: 1-Laryngyscopic examination 2-Acoustic analysis

Group II

Group II will comprise of 30 controls.

Other: 1-Laryngyscopic examination 2-Acoustic analysis

Interventions

1-Laryngyscopic examination 2-Acoustic analysis OTHER

1. History taking. 2. voice sample by recording (in sustained vowel \|a\| ) 3. Auditory Perceptual Assessment (APA): (Kotby et al., 1986) 4. Laryngyscopic examination: Patients will taken to a room with a tower on which the 8.5 mm 70 rigid laryngoscope (KARL STORZ - endoscope) (Tele pack X LED). 5. Acoustic analysis: The voice sample will be subjected to computerized acoustic analysis using Multidimensional voice program software(MDVP).

Group I; Group II

Eligibility Criteria

• Age: 10 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study will include 60 volunteers. They will divided into 2 groups. Group I will comprise of the 30 patients with Behçet's disease (BD), and Group II will comprise of 30 controls.

You may not qualify if:

• other autoimmune diseases.

Sponsors & Collaborators

• Minia University: lead

MeSH Terms

Conditions

Behcet Syndrome

Condition Hierarchy (Ancestors)

Mouth Diseases; Stomatognathic Diseases; Uveitis, Anterior; Panuveitis; Uveitis; Uveal Diseases; Eye Diseases; Vasculitis; Vascular Diseases; Cardiovascular Diseases; Hereditary Autoinflammatory Diseases; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin Diseases, Genetic; Skin Diseases; Skin and Connective Tissue Diseases; Skin Diseases, Vascular

Central Study Contacts

Wafaa Helmy Abd El-hakeem, MD

CONTACT

01091813874; dr.fofahma@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: doctor

Study Record Dates

• First Submitted: February 6, 2025
• First Posted: February 20, 2025
• Study Start: February 15, 2025
• Primary Completion: May 15, 2025
• Study Completion: June 1, 2025
• Last Updated: February 20, 2025

Record last verified: 2025-02