Reconstruction of Diffusely Diseased Left Anterior Descending with Left Internal Mammary Artery On-lay Patch or Saphenous Vein Patch Without Endarterectomy by Opening the Whole Wall of the Diseased Segment(s) Has Less Risk and Fewer Complications Compared to Endarterectomy Technique
Different Surgical Strategies for Management of Severely Diseased Left Anterior Descending Artery During Coronary Artery Bypasses Grafting
1 other identifier
interventional
90
0 countries
N/A
Brief Summary
The objective of this study is to compare different surgical strategies for management of severely diseased LAD artery during CABG i.e. LIMA on-lay patch vs. saphenous vein patch and the distal in situ LIMA and saphenous vein graft (LIMA+ SVG).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Dec 2025
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 9, 2024
CompletedFirst Posted
Study publicly available on registry
February 19, 2025
CompletedStudy Start
First participant enrolled
December 10, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 10, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
January 10, 2027
February 19, 2025
February 1, 2025
1 year
December 9, 2024
February 15, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Serum troponin level
Measure serum troponin level after 48h , after 1 week and after 1 month
From enrollment to 1 month after intervention
Study Arms (1)
Management of severly diseased LAD
EXPERIMENTALDifferent surgical strategies for management of severly diseased LAD
Interventions
Left internal mammary artery harvesting with on lay patch on left anterior descending coronary artery
Safenous vein patch on left anterior descending artery
Eligibility Criteria
You may qualify if:
- included patients with long-segment diffusely diseased LAD, with good ejection fraction and elective surgery.
You may not qualify if:
- Patients with associated valve surgery, left ventricular EF less than 40%, and severe comorbidities (renal or liver failure), preoperative dialysis, and hemodynamic instability, emergency operations were excluded.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
December 9, 2024
First Posted
February 19, 2025
Study Start
December 10, 2025
Primary Completion (Estimated)
December 10, 2026
Study Completion (Estimated)
January 10, 2027
Last Updated
February 19, 2025
Record last verified: 2025-02