Comparison of 30-day Morbidity and Mortality in Cancer Patients Based on Emergency Department Location

NCT06834646 | Recruiting

• 2 other identifiers: APHP240971IDRCB: 2024-A01679-38
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

Patients being followed for cancer account for 2.8% of emergency admissions in France. An acute episode that triggers a visit to the emergency department may be related to the progression of the disease, or to complications of treatment. The management of these patients is often complex and requires a degree of expertise. Emergency departments specialising in the management of cancer complications have been set up, and now deal exclusively with patients treated at their centres. However, for geographical or logistical reasons, patients with cancer are likely to consult a non-specialist emergency department and/or one located outside the cancer care centre. In this case, the emergency doctor may not have access to the oncology file, and care in the emergency department and downstream services may be sub-optimal. Studies have shown a positive impact on the quality of care and prognosis of patients thanks to the cancer centre's expertise. However, the effect of the centre on a cancer patient who visits the emergency department has never been studied. This is particularly true if the emergency department where the patient is seen is located in the cancer follow-up centre. The primary objective of the COVER study is to investigate the impact of the location of the emergency department where the patient is seen for their prognosis.

Conditions

Cancer; Cancer Remission

Keywords

Emergency Department; Cancer; Mortality; morbidity and mortality in Cancer

Outcome Measures

Primary Outcomes (1)

• Number of days alive spent outside the hospital

  1 month

Secondary Outcomes (9)

• Occurrence of a new/ unscheduled consultation

  30 days

• Length of hospitalisation

  90 day

• Unscheduled consultation or hospitalization emergency department discharge

  7 days

• Unexpected death

  7 days

• Secondary admission to the intensive care unit during the initial hospitalization following the emergency visit

  7 days

Study Arms (2)

Patients who visit the ED of the refereing oncologic hospital

Patients who visit another ED

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients followed for cancer and consulting the emergency department

You may qualify if:

• Patients aged 18 or over admitted to an emergency department with cancer that has been active or in remission for less than a year.

You may not qualify if:

• \- Opposition to participate in the study

Sponsors & Collaborators

• Assistance Publique - Hôpitaux de Paris: lead

Study Sites (1)

Hôpital Pitié Salpêtrière Emergency department

Paris, 75013, France

RECRUITING

MeSH Terms

Conditions

Neoplasms; Emergencies

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Yonathan FREUND, PU-PH

CONTACT

00 33 (0) 184827129; yonathan.freund@aphp.fr

Olivier PEYRONY, MD, PhD

CONTACT

00 33 (0) 142494939; olivier.peyrony@aphp.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 5, 2025
• First Posted: February 19, 2025
• Study Start: April 12, 2025
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): September 1, 2026
• Last Updated: January 20, 2026

Record last verified: 2026-01

Locations

FR (1)