Patient Preferences in Empathetic Communication by AI vs Human Authorship

NCT06832891 | Completed

• 1 other identifier: 24-010821
• Study Type: observational
• Target: 202
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate whether patients have different preference patterns for empathetic communication through AI vs human-being when knowledge of authorship is known vs blinded.

Conditions

Preference, Patient

Keywords

AI

Outcome Measures

Primary Outcomes (1)

• Preference patterns for empathetic communication

  Assessed by a brief survey: patients will be show two brief empathetic statements related to their serious illness diagnosis (Cancer), one generated by Artificial Intelligence (AI) and one generated by a human physician in palliative care who were both given the same writing instructions and generated their responses independently. Half of the surveys will label which statement is generated by human or AI unblinded group) and the other half will be blinded to statement authorship. Preference will be compared between the blinded and unblinded groups.

  Baseline

Study Arms (2)

Survey Group - Blinded

Participants will be blinded to origin of survey statements

Other: Survey

Survey Group - Unblinded

Participants will be informed of origin of survey statements

Other: Survey

Interventions

Survey OTHER

Patients complete survey

Survey Group - Blinded; Survey Group - Unblinded

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients over the age of 18 being seen in palliative care clinic who have already established care and with diagnosis of any malignancy

You may qualify if:

• Patients over the age of 18 being seen in palliative care clinic who have already established care and with diagnosis of any malignancy

You may not qualify if:

• Inability to consent defined as: Acute mental status changes (delirium/encephalopathy), acute substance intoxication, intellectual disability, dementia, patient with active legal guardian
• Major psychiatric disorders including, but not limited to, bipolar disorder, psychotic disorders, active substance use disorder, and patients with active suicidal or homicidal thoughts.
• NOTE: Patients with history of normal grieving reactions, major unipolar depressive disorder, posttraumatic stress disorder or generalized anxiety disorder would NOT be excluded.
• Inability to read in English

Sponsors & Collaborators

• Mayo Clinic: lead

Study Sites (1)

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

Location

Related Links

• Mayo Clinic Clinical Trials

MeSH Terms

Conditions

Patient Preference

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Patient Satisfaction; Treatment Adherence and Compliance; Health Behavior; Behavior

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• April Christensen, MD, MS

  Mayo Clinic in Rochester

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 13, 2025
• First Posted: February 18, 2025
• Study Start: April 21, 2025
• Primary Completion: June 30, 2025
• Study Completion: June 30, 2025
• Last Updated: August 14, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)