Efficacy of Baduanjin Exercise in COVID-19 Contraction Patients With Idiopathic Chronic Fatigue

NCT06829940 | Recruiting

• 1 other identifier: P.T.REC/012/005517
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Post-COVID recovery is associated with reduced functional fitness/capacity, low quality of life, and physical disabilities in those who survived after contracting the disease. The unpleasant symptoms of chronic post-viral/post-COVID syndrome (chronic fatigue perception, variant nonspecific myalgia, bad mood or depression, and insomnia or sleep disturbances) usually magnify the symptoms of already existing previously diagnosed concurrent untreatable chronic disorders , including the idiopathic chronic fatigue (ICF).(Leszczak et al., 2024) Baduanjin exercise training (BET) is one of the Chinese traditional Health-Qigong exercises that not only integrate slow coordinating postures/positions, breathing techniques, musculoskeletal stretching movements/positions, and meditative mind but also plays a strong role concerning health benefits (e.g. musculoskeletal pain-reducing, sleep disturbance-enhancing effects, and fatigue-reducing effects) (Zou et al., 2018).

Conditions

Chronic COVID-19 Syndrome

Outcome Measures

Primary Outcomes (1)

• Pulmonary function: By Spirometry Device:

  • Pulmonary function: By Spirometry Device: it measure ventilatory functions. forced vital capacity (FVC)

  By Spirometry Device: forced vital capacity will be measured at baseline, and it will be measured after twelve weeks again

Secondary Outcomes (10)

• Pulmonary function: By Spirometry Device:

  By Spirometry Device forced expiratory volume in one second (FEV1) will be measured at baseline, and it will be measured after twelve weeks again

• Measuring functional capacity: By Six-minute walk test (6MWT)

  Measuring functional capacity: By Six-minute walk test (6MWT)::will be measured at baseline, and it will be measured again after twelve weeks

• Modified Borg dyspnea scale (MBDS)

  Modified Borg dyspnea scale (MBDS) will be measured at baseline, and it will be measured again after twelve weeks

• Strength of lower limb muscles By a thirty-second sit-to-stand test

  thirty-second sit-to-stand test will be measured at baseline, and it will be measured again after twelve weeks

• Endurance of upper limb muscles: by the maximal repetitions of push-ups (MRPU).

  the maximal repetitions of push-ups (MRPU). will be measured at baseline, and it will be measured again after twelve weeks

Study Arms (2)

Baduanjin exercise training

EXPERIMENTAL

Each BET session consisted of a 10-minute warm-up and a 10-minute cool-down period \[Xia et al., 2023\]. These were followed by a 40-minute BET segment, which typically involved eight distinct body postures. These postures are based on the "Health Qigong Baduanjin Standard," as outlined in Zhao et al. \[2019\] and Koh \[1982\]. The eight postures are: (1) Support the Heaven, (2) Draw a Bow to Each Side, (3) Hold Up a Single Hand, (4) Practice Looking Back, (5) Shake the Hand and Wag the Tail, (6) Touch the Feet with Both Hands, (7) Climbing with Both Hands, and (8) Relax the Back, as explained in Zeng et al. \[2020\]

Other: Baduanjin exercise training (BET)

waitlist

NO INTERVENTION

this group will receive no intervention

Interventions

Baduanjin exercise training (BET) OTHER

Baduanjin Exercise Training (BET) is a traditional Chinese exercise focused on improving physical health, flexibility, balance, and mental well-being. It involves a 10-minute warm-up, a 40-minute core session practicing eight distinct postures, and a 10-minute cool-down. The postures, based on the Baduanjin form, target different body parts and promote strength, flexibility, and circulation. The exercises are synchronized with deep breathing to enhance relaxation and stress reduction. BET is especially beneficial for joint health, mobility, and mental clarity, making it suitable for individuals of all ages and fitness levels

Baduanjin exercise training

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• 40 patients will be recruited in the study.
• age ≥ 18 to ≤ 50 years old
• achieved three diagnostic items/criteria of ICF will be included in this BET trial: Fatigue lasting over 6 months, which significantly limits daily activities, reducing the person's usual activity level by more than 50%, as confirmed by a doctor.
• At least three of the following symptoms:
• Generalized muscle weakness Difficulty sleeping Frequent headaches A painful throat Muscle tenderness throughout the body Migratory joint pain Swollen lymph nodes in the neck or armpits Fatigue lasting more than a day after typical activities

You may not qualify if:

• Patients with a history of medical or complementary treatments for ICF disorder in the 6 months before contracting COVID or after recovery.
• Individuals who have engaged in therapeutic exercise, pharmacological treatments, or complementary therapies for post-COVID symptoms within the last six months prior to enrollment.
• ICF patients regularly using antidepressants or antipsychotics were excluded.
• Those who take sleeping pills regularly were also excluded.
• Patients with autoimmune diseases, malignant conditions, anemia, endocrine disorders, systemic diseases, or osteoarthritis affecting the cervical spine, lumbar region, or limbs were excluded.
• Individuals with abnormal results in laboratory tests, including neurological, neurophysiological, cardiological, liver/kidney function tests, or urine/stool analyses (as determined by a physician) were excluded.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo University

Cairo, 11432, Egypt

RECRUITING

Study Officials

• Alaa El-moatasem, lecturer

  Cairo University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Alaa El-moatasem, lecturer

CONTACT

01006625054; alaamotasem@cu.edu.eg

Rania ali, assistant professor

CONTACT

010015931155; roni.diamond8@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer of physical therapy

Study Record Dates

• First Submitted: February 14, 2025
• First Posted: February 17, 2025
• Study Start: October 9, 2024
• Primary Completion: February 22, 2025
• Study Completion: March 1, 2025
• Last Updated: February 17, 2025

Record last verified: 2025-02

Locations

EG (1)